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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4tvj 09L Poly [ADP-ribose] polymerase 2 2.4.2.30

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4tvj 09LPoly [ADP-ribose] polymerase 2 2.4.2.30 1.001
5ds3 09LPoly [ADP-ribose] polymerase 1 2.4.2.30 0.881
3c49 KU8Poly [ADP-ribose] polymerase 3 2.4.2.30 0.719
4tjy 3GNTankyrase-2 2.4.2.30 0.714
4tkg 09LTankyrase-2 2.4.2.30 0.711
4gv7 MEWPoly [ADP-ribose] polymerase 1 2.4.2.30 0.707
4hhz 15SPoly [ADP-ribose] polymerase 1 2.4.2.30 0.707
4pnm NU1Tankyrase-2 2.4.2.30 0.703
5dsy UHBPoly [ADP-ribose] polymerase 2 2.4.2.30 0.690
1efy BZCPoly [ADP-ribose] polymerase 1 2.4.2.30 0.684
4pnr G18Tankyrase-2 2.4.2.30 0.684
4gv2 5MEPoly [ADP-ribose] polymerase 3 2.4.2.30 0.683
2rd6 78PPoly [ADP-ribose] polymerase 1 2.4.2.30 0.680
3gn7 3GNPoly [ADP-ribose] polymerase 1 2.4.2.30 0.678
4avu LDRTankyrase-2 2.4.2.30 0.676
4gv4 MEJPoly [ADP-ribose] polymerase 3 2.4.2.30 0.673
4gv0 8MEPoly [ADP-ribose] polymerase 3 2.4.2.30 0.671
1pax DHQPoly [ADP-ribose] polymerase 1 2.4.2.30 0.670
3l3m A92Poly [ADP-ribose] polymerase 1 2.4.2.30 0.670
4avw G18Tankyrase-2 2.4.2.30 0.662
4f1q 0RZPoly [ADP-ribose] polymerase 14 2.4.2.30 0.661
4buw F33Tankyrase-2 2.4.2.30 0.659
4but 31FTankyrase-2 2.4.2.30 0.658
4buu F38Tankyrase-2 2.4.2.30 0.658
4bux F35Tankyrase-2 2.4.2.30 0.658
4hki FLNTankyrase-2 2.4.2.30 0.657
4bue JQFTankyrase-2 2.4.2.30 0.656
4bus 32FTankyrase-2 2.4.2.30 0.656
4bu9 08CTankyrase-2 2.4.2.30 0.655