Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4r5w XAV Poly [ADP-ribose] polymerase 1 2.4.2.30

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4r5w XAVPoly [ADP-ribose] polymerase 1 2.4.2.30 0.941
3c4h DRLPoly [ADP-ribose] polymerase 3 2.4.2.30 0.746
4gv4 MEJPoly [ADP-ribose] polymerase 3 2.4.2.30 0.734
4gv7 MEWPoly [ADP-ribose] polymerase 1 2.4.2.30 0.727
4gv2 5MEPoly [ADP-ribose] polymerase 3 2.4.2.30 0.721
5ds3 09LPoly [ADP-ribose] polymerase 1 2.4.2.30 0.719
3kr8 XAVTankyrase-2 2.4.2.30 0.718
4bud 29FTankyrase-2 2.4.2.30 0.717
2rcw AAIPoly [ADP-ribose] polymerase 1 2.4.2.30 0.708
3ce0 P34Poly [ADP-ribose] polymerase 3 2.4.2.30 0.708
2rd6 78PPoly [ADP-ribose] polymerase 1 2.4.2.30 0.707
4bue JQFTankyrase-2 2.4.2.30 0.707
4bu9 08CTankyrase-2 2.4.2.30 0.706
4bux F35Tankyrase-2 2.4.2.30 0.703
4buv 16ITankyrase-2 2.4.2.30 0.700
3l3m A92Poly [ADP-ribose] polymerase 1 2.4.2.30 0.698
1pax DHQPoly [ADP-ribose] polymerase 1 2.4.2.30 0.697
4hhz 15SPoly [ADP-ribose] polymerase 1 2.4.2.30 0.697
4buu F38Tankyrase-2 2.4.2.30 0.695
4pnr G18Tankyrase-2 2.4.2.30 0.695
3c49 KU8Poly [ADP-ribose] polymerase 3 2.4.2.30 0.693
4avu LDRTankyrase-2 2.4.2.30 0.692
4avw G18Tankyrase-2 2.4.2.30 0.690
4bui W2ETankyrase-2 2.4.2.30 0.688
1efy BZCPoly [ADP-ribose] polymerase 1 2.4.2.30 0.685
4buf F36Tankyrase-2 2.4.2.30 0.685
4tkg 09LTankyrase-2 2.4.2.30 0.685
4buw F33Tankyrase-2 2.4.2.30 0.684
3l3l L3LPoly [ADP-ribose] polymerase 1 2.4.2.30 0.682
4bjb P34Tankyrase-2 2.4.2.30 0.665
4f1l 0RYPoly [ADP-ribose] polymerase 14 2.4.2.30 0.665
3u9y 09LTankyrase-2 2.4.2.30 0.663
2zit NADExotoxin A 2.4.2.36 0.662
4bus 32FTankyrase-2 2.4.2.30 0.662
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.660
4e5i 0N9Polymerase acidic protein / 0.660
4li6 1XOTankyrase-1 2.4.2.30 0.659
3b78 NADExotoxin A 2.4.2.36 0.654
4e5f 0N7Polymerase acidic protein / 0.653
4l2f 1V3Tankyrase-2 2.4.2.30 0.652
4hkk AGITankyrase-2 2.4.2.30 0.651
1uk0 FRMPoly [ADP-ribose] polymerase 1 2.4.2.30 0.650
4bj9 UHBTankyrase-2 2.4.2.30 0.650