Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4hlh 20D Tankyrase-2 2.4.2.30

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4hlh 20DTankyrase-2 2.4.2.30 0.901
4kzl 20DTankyrase-2 2.4.2.30 0.888
4hlk 431Tankyrase-2 2.4.2.30 0.876
4kzu A73Tankyrase-2 2.4.2.30 0.871
4l0v 1V1Tankyrase-2 2.4.2.30 0.870
4bu9 08CTankyrase-2 2.4.2.30 0.852
4l0s 1UZTankyrase-2 2.4.2.30 0.843
4hlm 16STankyrase-2 2.4.2.30 0.840
4l0t 1V0Tankyrase-2 2.4.2.30 0.840
4bus 32FTankyrase-2 2.4.2.30 0.838
4l34 1VGTankyrase-2 2.4.2.30 0.838
4buf F36Tankyrase-2 2.4.2.30 0.836
4l09 1URTankyrase-2 2.4.2.30 0.836
4l10 A63Tankyrase-2 2.4.2.30 0.836
4l0i 1UWTankyrase-2 2.4.2.30 0.833
4bs4 A64Tankyrase-2 2.4.2.30 0.831
4hki FLNTankyrase-2 2.4.2.30 0.824
4buv 16ITankyrase-2 2.4.2.30 0.822
4hlf 15ZTankyrase-2 2.4.2.30 0.819
4l33 F70Tankyrase-2 2.4.2.30 0.819
4bue JQFTankyrase-2 2.4.2.30 0.815
4l31 F08Tankyrase-2 2.4.2.30 0.814
4bud 29FTankyrase-2 2.4.2.30 0.810
4bui W2ETankyrase-2 2.4.2.30 0.807
4but 31FTankyrase-2 2.4.2.30 0.807
4buu F38Tankyrase-2 2.4.2.30 0.807
4hlg 20BTankyrase-2 2.4.2.30 0.803
4bux F35Tankyrase-2 2.4.2.30 0.802
5aku 29FTankyrase-2 2.4.2.30 0.802
3kr8 XAVTankyrase-2 2.4.2.30 0.801
4l2k 1V8Tankyrase-2 2.4.2.30 0.798
4hkk AGITankyrase-2 2.4.2.30 0.794
4buw F33Tankyrase-2 2.4.2.30 0.793
4l32 1VFTankyrase-2 2.4.2.30 0.792
4hmh F94Tankyrase-2 2.4.2.30 0.790
4hl5 15WTankyrase-2 2.4.2.30 0.777
4l2f 1V3Tankyrase-2 2.4.2.30 0.769
4l2g 1V4Tankyrase-2 2.4.2.30 0.768
4hkn LU2Tankyrase-2 2.4.2.30 0.761
4avw G18Tankyrase-2 2.4.2.30 0.733
4avu LDRTankyrase-2 2.4.2.30 0.722
4bjb P34Tankyrase-2 2.4.2.30 0.700
3p0p NNFTankyrase-2 2.4.2.30 0.691
4gv4 MEJPoly [ADP-ribose] polymerase 3 2.4.2.30 0.681
4gv2 5MEPoly [ADP-ribose] polymerase 3 2.4.2.30 0.675
4msk 2C8Tankyrase-1 2.4.2.30 0.675
2z1x PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.667
4pnr G18Tankyrase-2 2.4.2.30 0.667
4gcx PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.664
2pwu GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.663
1p0e PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.662
2pot GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.662
3c4h DRLPoly [ADP-ribose] polymerase 3 2.4.2.30 0.662
4gv7 MEWPoly [ADP-ribose] polymerase 1 2.4.2.30 0.662
4hvx QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.662
4i9i 1DYTankyrase-1 2.4.2.30 0.662
3bld PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.661
4bj9 UHBTankyrase-2 2.4.2.30 0.661
1efz PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.660
1v2h GUNPurine nucleoside phosphorylase 2.4.2.1 0.660
2puc GUNHTH-type transcriptional repressor PurR / 0.660
4e5f 0N7Polymerase acidic protein / 0.660
4e5i 0N9Polymerase acidic protein / 0.660
4e5l DBHPolymerase acidic protein / 0.660
4hqv QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1ozq PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.659
4tjy 3GNTankyrase-2 2.4.2.30 0.659
4bjc RPBTankyrase-2 2.4.2.30 0.658
4h7z GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.658