Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3mdd FAD Medium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3mdd FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 1.506
4p13 FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 1.246
2vig FADShort-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.1 1.136
1jqi FADShort-chain specific acyl-CoA dehydrogenase, mitochondrial / 1.114
3oib FDAPutative acyl-CoA dehydrogenase / 1.103
1egd FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 1.081
2pg0 FADAcyl-CoA dehydrogenase / 1.049
3p4t FAOPutative acyl-CoA dehydrogenase / 1.031
4m9a FDAAcyl-CoA dehydrogenase / 1.027
3pfd FDAAcyl-CoA dehydrogenase FadE25 / 1.019
1rx0 FADIsobutyryl-CoA dehydrogenase, mitochondrial 1.3.99 0.998
4iv6 FDAIsovaleryl-CoA dehydrogenase / 0.990
2a1t FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.962
3nf4 FADAcyl-CoA dehydrogenase domain-containing protein / 0.951
5jsc FADPutative acyl-CoA dehydrogenase / 0.946
3r7k FDAProbable acyl CoA dehydrogenase / 0.944
1t9g FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.929
3sf6 FDAGlutaryl-CoA dehydrogenase / 0.924
4x28 FDAAcyl-CoA dehydrogenase FadE26 / 0.919
4x28 FDAAcyl-CoA dehydrogenase FadE27 / 0.919
5af7 FADAcyl-CoA dehydrogenase / 0.909
2dvl FADAcyl-CoA dehydrogenase / 0.901
3owa FADAcyl-CoA dehydrogenase / 0.897
5ahs FADAcyl-CoA dehydrogenase / 0.893
1u8v FAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase / 0.886
2eba FADPutative glutaryl-CoA dehydrogenase / 0.872
2d29 FADAcyl-CoA dehydrogenase / 0.851
2ix5 FADAcyl-coenzyme A oxidase 4, peroxisomal 1.3.3.6 0.845
1udy FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.842
1ege FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.838
4y9l FADAcyl-CoA dehydrogenase family member 11 / 0.838
1buc FADAcyl-CoA dehydrogenase, short-chain specific 1.3.8.1 0.830
3mpi FADGlutaryl-CoA dehydrogenase 1.3.99.32 0.816
1r2j FADFkbI / 0.806
2z1q FADAcyl-CoA dehydrogenase / 0.797
3u33 FADPutative acyl-CoA dehydrogenase AidB 1.3.99 0.786
3mpj FADGlutaryl-CoA dehydrogenase 1.3.99.32 0.738
2wzw FMNNitroreductase NfnB / 0.733
3eo8 FMNPutative nitroreductase / 0.731
3gh8 FMNIodotyrosine deiodinase 1 1.21.1.1 0.731
2fon FADAcyl-coenzyme A oxidase / 0.730
4ttc FMNIodotyrosine deiodinase 1 / 0.718
3djl FADPutative acyl-CoA dehydrogenase AidB 1.3.99 0.716
1siq FADGlutaryl-CoA dehydrogenase, mitochondrial 1.3.8.6 0.713
2yyi FAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component 1.14.14.9 0.708
2yyl FAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component 1.14.14.9 0.706
2bkj FMNNADPH-flavin oxidoreductase / 0.705
4kto FADPutative isovaleryl-CoA dehydrogenase protein / 0.703
1vfr FMNMajor NAD(P)H-flavin oxidoreductase 1.6.99 0.695
4kuk RBFPutative blue-light photoreceptor / 0.695
2hsa FMN12-oxophytodienoate reductase 3 1.3.1.42 0.687
3gag FMNPutative NADH dehydrogenase NAD(P)H nitroreductase / 0.687
3e39 FMNNitroreductase / 0.686
3gfd FMNIodotyrosine deiodinase 1 1.21.1.1 0.686
4qly FMNEnone reductase CLA-ER / 0.686
2isl FNR5,6-dimethylbenzimidazole synthase 1.13.11.79 0.685
2pr5 FMNBlue-light photoreceptor / 0.682
1bwl FMNNADPH dehydrogenase 1 1.6.99.1 0.681
4opt FDAConserved Archaeal protein / 0.679
1bwk FMNNADPH dehydrogenase 1 1.6.99.1 0.677
2reh FADNitroalkane oxidase 1.7.3.1 0.676
1icp FMN12-oxophytodienoate reductase 1 1.3.1.42 0.675
2c12 FADNitroalkane oxidase 1.7.3.1 0.674
2v18 FMNDodecin / 0.674
2z6d FMNPhototropin-2 2.7.11.1 0.673
4eo3 FMNBacterioferritin comigratory protein/NADH dehydrogenase / 0.673
3hgs FMN12-oxophytodienoate reductase 3 1.3.1.42 0.672
2gou FMNNADH:flavin oxidoreductase Sye1 / 0.669
4tmb FMNOld yellow enzyme / 0.669
2y48 FADLysine-specific histone demethylase 1A 1 0.668
3ge6 FMNNitroreductase / 0.664
1vhn FMNtRNA-dihydrouridine synthase / 0.662
3pxv FMNNitroreductase / 0.662
1h83 FADPolyamine oxidase 1.5.3.14 0.661
1ics FMN12-oxophytodienoate reductase 1 1.3.1.42 0.660
1oyc FMNNADPH dehydrogenase 1 1.6.99.1 0.660
3n19 FNRXenobiotic reductase / 0.660
3hgr FMN12-oxophytodienoate reductase 1 1.3.1.42 0.659
2isk FNR5,6-dimethylbenzimidazole synthase 1.13.11.79 0.658
1jeh FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.657
3ic9 FADPutative dihydrolipoamide dehydrogenase / 0.656
3gdp FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.655
2vxa RBFDodecin / 0.654
3gsi FADDimethylglycine oxidase 1.5.3.10 0.653
3utg FDAUDP-galactopyranose mutase / 0.652
3w8w FADPutative FAD-dependent oxygenase EncM / 0.650