Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3f1k NAP Uncharacterized oxidoreductase YciK 1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3f1k NAPUncharacterized oxidoreductase YciK 1 1.073
3gy0 NAPNAD(P)-dependent oxidoreductase / 0.858
3iah NAPPutative oxoacyl-(Acyl carrier protein) reductase / 0.832
4j7x NAPSepiapterin reductase 1.1.1.153 0.804
4hp8 NAP2-deoxy-D-gluconate 3-dehydrogenase / 0.778
1w8d NAP2,4-dienoyl-CoA reductase, mitochondrial 1.3.1.34 0.775
3r3s NADPutative oxidoreductase / 0.766
3bhi NAPCarbonyl reductase [NADPH] 1 1.1.1.184 0.764
5jyd NADShort chain dehydrogenase / 0.758
4j7u NAPSepiapterin reductase 1.1.1.153 0.746
4z3d NDPCarbonyl reductase [NADPH] 1 1.1.1.184 0.746
4fj0 NAP17beta-hydroxysteroid dehydrogenase / 0.742
4hbg NDP3-oxoacyl-[acyl-carrier-protein] reductase 1.1.1.100 0.742
4fj1 NAP17beta-hydroxysteroid dehydrogenase / 0.741
1w73 NAP2,4-dienoyl-CoA reductase, mitochondrial 1.3.1.34 0.740
4fj2 NAP17beta-hydroxysteroid dehydrogenase / 0.738
4fc7 NAPPeroxisomal 2,4-dienoyl-CoA reductase 1.3.1.34 0.737
4hwk NAPSepiapterin reductase 1.1.1.153 0.737
2d1y NADOxidoreductase, short-chain dehydrogenase/reductase family / 0.730
4k6f NAPPutative Acetoacetyl-CoA reductase / 0.730
3p19 NDPPutative blue fluorescent protein / 0.724
3qwf NAP17beta-hydroxysteroid dehydrogenase / 0.720
1sny NAPLD36273p / 0.719
1oaa NAPSepiapterin reductase 1.1.1.153 0.718
4u7w NDPMxaA / 0.717
3sxp NADADP-L-glycero-D-mannoheptose-6-epimerase / 0.716
1xg5 NAPDehydrogenase/reductase SDR family member 11 / 0.715
4pvd NDPNADPH-dependent methylglyoxal reductase GRE2 / 0.715
3u4c NDPNADPH-dependent reductase BacG / 0.711
2b4q NAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase 1.1.1.100 0.710
2nnl NAPDihydroflavonol 4-reductase 1.1.1.219 0.709
4b79 NADProbable short-chain dehydrogenase / 0.708
3o26 NDPSalutaridine reductase / 0.704
5idw NAPShort-chain dehydrogenase/reductase SDR / 0.703
4bms NAPAlclohol dehydrogenase/short-chain dehydrogenase / 0.702
1ae1 NAPTropinone reductase 1 / 0.698
2c54 NADGDP-mannose 3,5-epimerase 5.1.3.18 0.696
2c59 NADGDP-mannose 3,5-epimerase 5.1.3.18 0.696
3aut NAIGlucose 1-dehydrogenase 4 1.1.1.47 0.695
5d2e NAPMlnE / 0.695
3rku NAPNADP-dependent 3-hydroxy acid dehydrogenase / 0.693
1x7g NAPPutative ketoacyl reductase 1.3.1 0.692
2bfo NDPPteridine reductase 1 1.5.1.33 0.691
1n5d NDPCarbonyl reductase [NADPH] 1 / 0.690
3l77 NJPShort-chain alcohol dehydrogenase / 0.689
3pgx NADUncharacterized NAD-dependent oxidoreductase MAP_4146 / 0.689
3tox NAPPutative oxidoreductase / 0.689
3o03 NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) / 0.685
3w8d NAD3-hydroxybutyrate dehydrogenase / 0.685
2wyv NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.684
4c7k NAPCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.684
1g6k NADGlucose 1-dehydrogenase 1.1.1.47 0.683
1h5q NAPNADP-dependent mannitol dehydrogenase 1.1.1.138 0.683
1rwb NADGlucose 1-dehydrogenase 1.1.1.47 0.679
1xse NDPCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.679
2b35 NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.679
2y99 NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase 1.3.1.56 0.679
3s55 NADPutative short-chain dehydrogenase/reductase / 0.679
1rkx NADCDP-D-glucose-4,6-dehydratase / 0.678
2gn8 NAPUDP-N-acetylglucosamine 4,6-dehydratase (inverting) 4.2.1.115 0.678
3vdq NAD3-hydroxybutyrate dehydrogenase / 0.678
1zem NADXylitol dehydrogenase / 0.677
1gco NADGlucose 1-dehydrogenase 1.1.1.47 0.675
3ai2 NDPNADPH-sorbose reductase / 0.675
3ehe NADUDP-glucose 4-epimerase (GalE-1) / 0.675
4bmv NAPShort-chain dehydrogenase / 0.675
5jsf NAD17-beta-hydroxysteroid dehydrogenase 14 1.1.1 0.675
1bws NDPGDP-L-fucose synthase / 0.673
1cyd NDPCarbonyl reductase [NADPH] 2 1.1.1.184 0.673
2ztu NADD(-)-3-hydroxybutyrate dehydrogenase / 0.673
3uce NDPDehydrogenase / 0.673
5cpb NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.673
1qyv NAPEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.672
2c29 NAPDihydroflavonol 4-reductase / 0.672
1gee NADGlucose 1-dehydrogenase 1.1.1.47 0.671
3icp NADNAD-dependent epimerase/dehydratase / 0.671
5jy1 NADPutative short-chain dehydrogenase/reductase / 0.671
1e3w NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.670
1pr9 NAPL-xylulose reductase 1.1.1.10 0.670
2hrb NAPCarbonyl reductase [NADPH] 3 1.1.1.184 0.670
2nv6 ZIDEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.670
3tn7 NJPShort-chain alcohol dehydrogenase / 0.670
4zju NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.670
3qrw NDPPutative ketoacyl reductase 1.3.1 0.669
3ruc NADUDP-N-acetylglucosamine 4-epimerase / 0.669
4bgi NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.669
2q1u NADPutative nucleotide sugar epimerase/ dehydratase / 0.668
3mje NDPAmphB / 0.668
1e7q NAPGDP-L-fucose synthase / 0.667
3ak4 NADNADH-dependent quinuclidinone reductase / 0.667
3oew NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.667
4o0l NDPNADPH-dependent 3-quinuclidinone reductase / 0.666
2ztv NADD(-)-3-hydroxybutyrate dehydrogenase / 0.665
4bii NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.665
4eso NAPPutative oxidoreductase / 0.665
4tqg NDPPutative dTDP-d-glucose 4 6-dehydratase / 0.664
3rua NADUDP-N-acetylglucosamine 4-epimerase / 0.663
3sj7 NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative / 0.663
3w8f NAD3-hydroxybutyrate dehydrogenase / 0.663
2ag5 NAD3-hydroxybutyrate dehydrogenase type 2 / 0.661
3a28 NADL-2,3-butanediol dehydrogenase 1.1.1.76 0.661
3ruf NADUDP-N-acetylglucosamine 4-epimerase / 0.661
1g0n NDPTetrahydroxynaphthalene reductase 1.1.1.252 0.660
4fda NAP3-oxoacyl-[acyl-carrier-protein] reductase 1.1.1.100 0.660
3tsc NADUncharacterized protein / 0.659
4clo NAPPteridine reductase / 0.659
5koi NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.659
2b37 NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.657
2q2v NADBeta-D-hydroxybutyrate dehydrogenase / 0.657
1geg NADDiacetyl reductase [(S)-acetoin forming] 1.1.1.304 0.656
2dkn NAI3-alpha-hydroxysteroid dehydrogenase / 0.656
3h4v NAPPteridine reductase 1 1.5.1.33 0.656
4m87 NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.656
3of2 NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.655
3wds NADNADH-dependent quinuclidinone reductase / 0.655
4dbz NDPPutative ketoacyl reductase 1.3.1 0.655
4hxy NDPPlm1 / 0.655
2aq8 NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.654
1e3s NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.653
3ko8 NADNAD-dependent epimerase/dehydratase / 0.653
3sju NDPKeto reductase / 0.653
1g1a NADdTDP-glucose 4,6-dehydratase / 0.652
3d3w NAPL-xylulose reductase 1.1.1.10 0.652
2ztl NADD(-)-3-hydroxybutyrate dehydrogenase / 0.651
4i5e NAPAlclohol dehydrogenase/short-chain dehydrogenase / 0.651
4oxy NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.651
1fxs NAPGDP-L-fucose synthase / 0.650
1n7h NDPGDP-mannose 4,6 dehydratase 2 4.2.1.47 0.650
2b36 NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.650
2ekp NAD2-deoxy-D-gluconate 3-dehydrogenase / 0.650
4qec NAPElxO / 0.650
4qed NAPElxO / 0.650