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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2q3e UPG UDP-glucose 6-dehydrogenase 1.1.1.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2q3e UPGUDP-glucose 6-dehydrogenase 1.1.1.22 1.479
3ptz UDXUDP-glucose 6-dehydrogenase 1.1.1.22 1.303
4edf UPGUDP-glucose 6-dehydrogenase 1.1.1.22 1.224
2qg4 UGAUDP-glucose 6-dehydrogenase 1.1.1.22 1.050
3khu UPGUDP-glucose 6-dehydrogenase 1.1.1.22 1.047
3gg2 UGASugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family / 1.001
3tdk UPGUDP-glucose 6-dehydrogenase 1.1.1.22 0.982
1dli UDXUDP-glucose 6-dehydrogenase / 0.935
1mv8 GDXGDP-mannose 6-dehydrogenase 1.1.1.132 0.832
1mfz GDXGDP-mannose 6-dehydrogenase 1.1.1.132 0.788
2y0d UGAUDP-glucose dehydrogenase / 0.776
1muu GDXGDP-mannose 6-dehydrogenase 1.1.1.132 0.733
1dlj UGAUDP-glucose 6-dehydrogenase / 0.710
5a02 NAPGlucose-fructose oxidoreductase / 0.680
3bgi SAHThiopurine S-methyltransferase 2.1.1.67 0.667
4avl TMPPolymerase acidic protein / 0.667
1nc1 MTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 3.2.2.9 0.664
1p6x THMThymidine kinase / 0.655
2rl1 UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase / 0.652
3amy AGICasein kinase II subunit alpha 2.7.11.1 0.652
5a03 NDPGlucose-fructose oxidoreductase / 0.652
5fsy AR6Uncharacterized protein / 0.650