Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2hdj NDP Aldo-keto reductase family 1 member C2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2hdj NDPAldo-keto reductase family 1 member C2 / 1.492
4jtq NAPAldo-keto reductase family 1 member C2 / 1.218
1q5m NDPProstaglandin-E(2) 9-reductase 1.1.1.189 1.214
4jq3 NAPAldo-keto reductase family 1 member C2 / 1.214
4l1x NAPAldo-keto reductase family 1 member C2 / 1.199
4xo7 NAPAldo-keto reductase family 1 member C2 / 1.176
4dz5 NAPAldo-keto reductase family 1 member C3 / 1.123
1s1p NAPAldo-keto reductase family 1 member C3 / 1.098
1s1r NAPAldo-keto reductase family 1 member C3 / 1.056
1k8c NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 1.033
3buv NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.998
3h7r NAPAldo-keto reductase family 4 member C8 / 0.997
4pmj NAPPutative oxidoreductase / 0.993
1hqt NAPAlcohol dehydrogenase [NADP(+)] 1.1.1.2 0.985
2fvl NAPAldo-keto reductase family 1 member C4 1.1.1.225 0.983
3dop NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.958
2bgs NDPAldose reductase 1.1.1.21 0.953
3bv7 NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.952
1ef3 NAPAldose reductase 1.1.1.21 0.951
3h7u NAPNADPH-dependent aldo-keto reductase, chloroplastic / 0.947
3g1r NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.944
4g5d NDPProstaglandin F synthase 1.1.1.188 0.935
1ads NAPAldose reductase 1.1.1.21 0.934
2acs NAPAldose reductase 1.1.1.21 0.927
3ln3 NADAldo-keto reductase family 1 member C13 / 0.919
3caq NDP3-oxo-5-beta-steroid 4-dehydrogenase / 0.914
1mi3 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.913
5c7h NDPPutative oxidoreductase / 0.912
1vp5 NAPOxidoreductase, aldo/keto reductase family / 0.907
2pev NDPAldose reductase 1.1.1.21 0.906
2iq0 NAPAldose reductase 1.1.1.21 0.903
1z8a NAPAldose reductase 1.1.1.21 0.902
2pf8 NDPAldose reductase 1.1.1.21 0.900
3q67 NAPAldose reductase 1.1.1.21 0.884
1ye6 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.880
3q65 NAPAldose reductase 1.1.1.21 0.877
3v36 NAPAldose reductase 1.1.1.21 0.877
3uzw NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.876
2vdg NDPAldose reductase 1.1.1.21 0.875
1x98 NAPAldose reductase 1.1.1.21 0.869
2j8t NAPAldose reductase 1.1.1.21 0.864
2acu NAPAldose reductase 1.1.1.21 0.859
4xzn NAPAldo-keto reductase family 1 member B10 1.1.1 0.858
1x96 NAPAldose reductase 1.1.1.21 0.857
1sm9 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.856
1a80 NDP2,5-diketo-D-gluconic acid reductase A 1.1.1.346 0.854
3qkz NAPAldose reductase-related protein 1 1.1.1.21 0.854
1ah4 NAPAldose reductase 1.1.1.21 0.850
4xzm NAPAldo-keto reductase family 1 member B10 1.1.1 0.838
1az2 NAPAldose reductase 1.1.1.21 0.834
2p5n NDPAldo-keto reductase family 1 member C21 1.1.1 0.826
4ijr NDPD-arabinose dehydrogenase [NAD(P)+] heavy chain 1.1.1.117 0.824
1ye4 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.823
3wcz NAPAldo-keto reductase AKR2E4 / 0.821
2acq NAPAldose reductase 1.1.1.21 0.818
1r38 NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.814
2pfh NDPAldose reductase 1.1.1.21 0.812
3o3r NAPAldose reductase-related protein 1 1.1.1.21 0.810
2hej NDPAldo-keto reductase family 1 member C21 1.1.1 0.801
2clp NDPAflatoxin B1 aldehyde reductase member 3 / 0.793
1z9a NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.778
1c9w NAPAldose reductase-related protein 2 / 0.777
3wg6 NDPNADPH-dependent conjugated polyketone reductase C1 / 0.755
1zgd NAPChalcone reductase / 0.728
3lut NAPVoltage-gated potassium channel subunit beta-2 / 0.723
1ye6 NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.714
1lqa NDPProtein tas / 0.703
4h8n NDPNADPH-dependent conjugated polyketone reductase C2 / 0.699
1m9h NAD2,5-diketo-D-gluconic acid reductase A 1.1.1.346 0.697
4aub NAPL-glyceraldehyde 3-phosphate reductase 1.1.1 0.694
1lwi NAP3-alpha-hydroxysteroid dehydrogenase 1.1.1.50 0.693
1qrq NDPVoltage-gated potassium channel subunit beta-2 / 0.687
2he5 NDPAldo-keto reductase family 1 member C21 1.1.1 0.687
2c91 NAPAflatoxin B1 aldehyde reductase member 2 / 0.686
4jtd NAPVoltage-gated potassium channel subunit beta-2 / 0.675
2r9r NAPVoltage-gated potassium channel subunit beta-2 / 0.674
1og6 NAPOxidoreductase YdhF 1 0.666
3wbw NDPPutative 2,5-diketo-D-gluconic acid reductase / 0.665
2io9 ADPBifunctional glutathionylspermidine synthetase/amidase / 0.657
2io7 ANPBifunctional glutathionylspermidine synthetase/amidase / 0.655
1pz0 NAPProtein IolS 1.1.1 0.653