Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ye6 NAP NAD(P)H-dependent D-xylose reductase 1.1.1.307

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1ye6 NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 1.230
1mi3 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.888
1r38 NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.879
1z9a NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.858
2pfh NDPAldose reductase 1.1.1.21 0.834
1q5m NDPProstaglandin-E(2) 9-reductase 1.1.1.189 0.832
4jq3 NAPAldo-keto reductase family 1 member C2 / 0.832
1sm9 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.821
3buv NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.817
3wg6 NDPNADPH-dependent conjugated polyketone reductase C1 / 0.811
1ye4 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.807
3caq NDP3-oxo-5-beta-steroid 4-dehydrogenase / 0.800
4pmj NAPPutative oxidoreductase / 0.799
4jtq NAPAldo-keto reductase family 1 member C2 / 0.795
3bv7 NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.791
4l1x NAPAldo-keto reductase family 1 member C2 / 0.785
3g1r NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.780
5c7h NDPPutative oxidoreductase / 0.780
1k8c NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.775
3q65 NAPAldose reductase 1.1.1.21 0.775
2bgs NDPAldose reductase 1.1.1.21 0.768
1s1r NAPAldo-keto reductase family 1 member C3 / 0.764
3dop NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.763
2bp1 NDPAflatoxin B1 aldehyde reductase member 2 / 0.756
1lwi NAP3-alpha-hydroxysteroid dehydrogenase 1.1.1.50 0.754
2fvl NAPAldo-keto reductase family 1 member C4 1.1.1.225 0.751
2hej NDPAldo-keto reductase family 1 member C21 1.1.1 0.749
1ye6 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.746
1ads NAPAldose reductase 1.1.1.21 0.743
1gve NAPAflatoxin B1 aldehyde reductase member 3 1 0.741
2pf8 NDPAldose reductase 1.1.1.21 0.741
3h7u NAPNADPH-dependent aldo-keto reductase, chloroplastic / 0.740
2acq NAPAldose reductase 1.1.1.21 0.739
4xo7 NAPAldo-keto reductase family 1 member C2 / 0.738
1ef3 NAPAldose reductase 1.1.1.21 0.733
3ln3 NADAldo-keto reductase family 1 member C13 / 0.732
1lqa NDPProtein tas / 0.728
4dz5 NAPAldo-keto reductase family 1 member C3 / 0.726
2pev NDPAldose reductase 1.1.1.21 0.725
1x96 NAPAldose reductase 1.1.1.21 0.720
4h8n NDPNADPH-dependent conjugated polyketone reductase C2 / 0.720
2j8t NAPAldose reductase 1.1.1.21 0.719
2he5 NDPAldo-keto reductase family 1 member C21 1.1.1 0.717
4ijr NDPD-arabinose dehydrogenase [NAD(P)+] heavy chain 1.1.1.117 0.716
2hdj NDPAldo-keto reductase family 1 member C2 / 0.714
4aub NAPL-glyceraldehyde 3-phosphate reductase 1.1.1 0.714
1z8a NAPAldose reductase 1.1.1.21 0.713
1s1p NAPAldo-keto reductase family 1 member C3 / 0.712
2acu NAPAldose reductase 1.1.1.21 0.712
4xzm NAPAldo-keto reductase family 1 member B10 1.1.1 0.712
2iq0 NAPAldose reductase 1.1.1.21 0.711
3h7r NAPAldo-keto reductase family 4 member C8 / 0.710
3q67 NAPAldose reductase 1.1.1.21 0.710
1x98 NAPAldose reductase 1.1.1.21 0.709
3uzw NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.707
1hqt NAPAlcohol dehydrogenase [NADP(+)] 1.1.1.2 0.706
3wcz NAPAldo-keto reductase AKR2E4 / 0.706
1a80 NDP2,5-diketo-D-gluconic acid reductase A 1.1.1.346 0.703
1ah4 NAPAldose reductase 1.1.1.21 0.703
3o3r NAPAldose reductase-related protein 1 1.1.1.21 0.700
1vp5 NAPOxidoreductase, aldo/keto reductase family / 0.695
2acs NAPAldose reductase 1.1.1.21 0.695
2vdg NDPAldose reductase 1.1.1.21 0.690
3qkz NAPAldose reductase-related protein 1 1.1.1.21 0.690
2p5n NDPAldo-keto reductase family 1 member C21 1.1.1 0.684
3v36 NAPAldose reductase 1.1.1.21 0.681
1m9h NAD2,5-diketo-D-gluconic acid reductase A 1.1.1.346 0.676
4xzn NAPAldo-keto reductase family 1 member B10 1.1.1 0.673
4jtd NAPVoltage-gated potassium channel subunit beta-2 / 0.668
1zgd NAPChalcone reductase / 0.667
2clp NDPAflatoxin B1 aldehyde reductase member 3 / 0.667
4jta NAPVoltage-gated potassium channel subunit beta-2 / 0.667
1og6 NAPOxidoreductase YdhF 1 0.665
5a04 NDPGlucose-fructose oxidoreductase / 0.661
5a06 NDPGlucose-fructose oxidoreductase / 0.661
4g5d NDPProstaglandin F synthase 1.1.1.188 0.659
1az2 NAPAldose reductase 1.1.1.21 0.651
1c9w NAPAldose reductase-related protein 2 / 0.650