Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1mi3 NAD NAD(P)H-dependent D-xylose reductase 1.1.1.307

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1mi3 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 1.403
1r38 NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 1.168
1sm9 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 1.167
1z9a NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 1.147
1ye4 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 1.133
1k8c NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 1.027
1ye6 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.957
2j8t NAPAldose reductase 1.1.1.21 0.954
1z8a NAPAldose reductase 1.1.1.21 0.925
2hdj NDPAldo-keto reductase family 1 member C2 / 0.913
2pf8 NDPAldose reductase 1.1.1.21 0.910
4ijr NDPD-arabinose dehydrogenase [NAD(P)+] heavy chain 1.1.1.117 0.906
4jq3 NAPAldo-keto reductase family 1 member C2 / 0.905
1s1p NAPAldo-keto reductase family 1 member C3 / 0.904
2pev NDPAldose reductase 1.1.1.21 0.894
3q65 NAPAldose reductase 1.1.1.21 0.894
2acq NAPAldose reductase 1.1.1.21 0.892
1ads NAPAldose reductase 1.1.1.21 0.888
1ye6 NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.888
3h7u NAPNADPH-dependent aldo-keto reductase, chloroplastic / 0.881
1x98 NAPAldose reductase 1.1.1.21 0.880
3q67 NAPAldose reductase 1.1.1.21 0.875
1x96 NAPAldose reductase 1.1.1.21 0.873
3wg6 NDPNADPH-dependent conjugated polyketone reductase C1 / 0.867
3uzw NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.864
4dz5 NAPAldo-keto reductase family 1 member C3 / 0.861
3v36 NAPAldose reductase 1.1.1.21 0.855
1c9w NAPAldose reductase-related protein 2 / 0.849
4g5d NDPProstaglandin F synthase 1.1.1.188 0.845
1ah4 NAPAldose reductase 1.1.1.21 0.838
2acs NAPAldose reductase 1.1.1.21 0.836
4xo7 NAPAldo-keto reductase family 1 member C2 / 0.833
1q5m NDPProstaglandin-E(2) 9-reductase 1.1.1.189 0.821
1gve NAPAflatoxin B1 aldehyde reductase member 3 1 0.818
2pfh NDPAldose reductase 1.1.1.21 0.817
4l1x NAPAldo-keto reductase family 1 member C2 / 0.817
2bp1 NDPAflatoxin B1 aldehyde reductase member 2 / 0.814
3bv7 NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.814
2acu NAPAldose reductase 1.1.1.21 0.809
4jtq NAPAldo-keto reductase family 1 member C2 / 0.807
4pmj NAPPutative oxidoreductase / 0.801
2bgs NDPAldose reductase 1.1.1.21 0.789
3g1r NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.787
1ef3 NAPAldose reductase 1.1.1.21 0.786
4xzn NAPAldo-keto reductase family 1 member B10 1.1.1 0.782
2iq0 NAPAldose reductase 1.1.1.21 0.779
1zgd NAPChalcone reductase / 0.766
3buv NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.766
3ln3 NADAldo-keto reductase family 1 member C13 / 0.765
1a80 NDP2,5-diketo-D-gluconic acid reductase A 1.1.1.346 0.753
1lqa NDPProtein tas / 0.751
3h7r NAPAldo-keto reductase family 4 member C8 / 0.750
4xzm NAPAldo-keto reductase family 1 member B10 1.1.1 0.750
3dop NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.748
3o3r NAPAldose reductase-related protein 1 1.1.1.21 0.748
1m9h NAD2,5-diketo-D-gluconic acid reductase A 1.1.1.346 0.745
1hqt NAPAlcohol dehydrogenase [NADP(+)] 1.1.1.2 0.744
4jta NAPVoltage-gated potassium channel subunit beta-2 / 0.743
1s1r NAPAldo-keto reductase family 1 member C3 / 0.740
2clp NDPAflatoxin B1 aldehyde reductase member 3 / 0.737
1az2 NAPAldose reductase 1.1.1.21 0.732
2he5 NDPAldo-keto reductase family 1 member C21 1.1.1 0.732
2vdg NDPAldose reductase 1.1.1.21 0.729
3qkz NAPAldose reductase-related protein 1 1.1.1.21 0.728
5c7h NDPPutative oxidoreductase / 0.724
3wcz NAPAldo-keto reductase AKR2E4 / 0.714
2hej NDPAldo-keto reductase family 1 member C21 1.1.1 0.710
1og6 NAPOxidoreductase YdhF 1 0.709
3caq NDP3-oxo-5-beta-steroid 4-dehydrogenase / 0.708
1lwi NAP3-alpha-hydroxysteroid dehydrogenase 1.1.1.50 0.702
1vp5 NAPOxidoreductase, aldo/keto reductase family / 0.701
1pz0 NAPProtein IolS 1.1.1 0.698
2c91 NAPAflatoxin B1 aldehyde reductase member 2 / 0.694
4h8n NDPNADPH-dependent conjugated polyketone reductase C2 / 0.679
1qrq NDPVoltage-gated potassium channel subunit beta-2 / 0.676
4aub NAPL-glyceraldehyde 3-phosphate reductase 1.1.1 0.667
3lut NAPVoltage-gated potassium channel subunit beta-2 / 0.665
3lnm NAPVoltage-gated potassium channel subunit beta-2 / 0.663
2fvl NAPAldo-keto reductase family 1 member C4 1.1.1.225 0.660
4jtd NAPVoltage-gated potassium channel subunit beta-2 / 0.660
2p5n NDPAldo-keto reductase family 1 member C21 1.1.1 0.659