Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.21.000
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.522
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.487
3zewSTUEphrin type-B receptor 42.7.10.10.483
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.472
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.472
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.468
4o0wADNAurora kinase A2.7.11.10.465
4qmlANPSerine/threonine-protein kinase 242.7.11.10.463
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.462
2c6eHPMAurora kinase A2.7.11.10.461
2j7t274Serine/threonine-protein kinase 102.7.11.10.461
5dt0SKEAurora kinase A2.7.11.10.459
4aotGW8Serine/threonine-protein kinase 102.7.11.10.456
4gk4L90Ephrin type-A receptor 32.7.10.10.455
1finATPCyclin-dependent kinase 22.7.11.220.454
2qoqANPEphrin type-A receptor 32.7.10.10.453
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.453
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.453
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.452
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.451
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.450
4nka2K7Fibroblast growth factor receptor 1/0.450
4f640S8Fibroblast growth factor receptor 1/0.448
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.448
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.447
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4gmy0X5Tyrosine-protein kinase JAK2/0.445
4nks2M2Fibroblast growth factor receptor 1/0.445
3js2VM1Fibroblast growth factor receptor 1/0.444
3w2sW2REpidermal growth factor receptor2.7.10.10.444
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.444
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
4jia1K3Tyrosine-protein kinase JAK2/0.443
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.442
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.442
2xvdAS6Ephrin type-B receptor 42.7.10.10.441
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.441
3begANPSRSF protein kinase 12.7.11.10.440
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.440