scPDB - Distribution of Cavity Similarity values of 4giy entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4giy	0WY	Queuine tRNA-ribosyltransferase	2.4.2.29

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
4giy	0WY	Queuine tRNA-ribosyltransferase	2.4.2.29	1.000
4fr1	0V2	Queuine tRNA-ribosyltransferase	2.4.2.29	0.769
3ge7	AFQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.619
4gh1	0WX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.590
4gg9	0WW	Queuine tRNA-ribosyltransferase	2.4.2.29	0.585
1q4w	DQU	Queuine tRNA-ribosyltransferase	2.4.2.29	0.580
1p0e	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.575
2bbf	344	Queuine tRNA-ribosyltransferase	2.4.2.29	0.562
3sm0	AEK	Queuine tRNA-ribosyltransferase	2.4.2.29	0.548
1y5x	E89	Queuine tRNA-ribosyltransferase	2.4.2.29	0.547
2qzr	S79	Queuine tRNA-ribosyltransferase	2.4.2.29	0.547
3gc4	AAQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.542
1f3e	DPZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.541
4gi4	0EX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.539
1q63	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.537
4gh3	0EV	Queuine tRNA-ribosyltransferase	2.4.2.29	0.535
2z1x	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.534
1y5w	NEZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.532
1y5v	NE8	Queuine tRNA-ribosyltransferase	2.4.2.29	0.529
1q65	BHB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.525
4fps	0UX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.521
4gkt	0O1	Queuine tRNA-ribosyltransferase	2.4.2.29	0.519
1k4h	APQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.516
2pot	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	0.516
4hsh	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.515
4gcx	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.512
4q8p	CKR	Queuine tRNA-ribosyltransferase	2.4.2.29	0.512
1ozq	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.507
1efz	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.495
1q66	KMB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.493
1k4g	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.489
4fsa	0V3	Queuine tRNA-ribosyltransferase	2.4.2.29	0.489
4hvx	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.484
2z1w	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.482
4ug5	H4B	Nitric oxide synthase oxygenase	1.14.13.165	0.471
5c6c	CMP	cGMP-dependent protein kinase 2	2.7.11.12	0.471
1ygk	RRC	Pyridoxal kinase	2.7.1.35	0.470
3biz	61E	Wee1-like protein kinase	2.7.10.2	0.467
2in6	839	Wee1-like protein kinase	2.7.10.2	0.466
4gki	0JN	Aminoglycoside 3'-phosphotransferase AphA1-IAB	/	0.466
4hqv	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.466
4fgc	PQ0	NADPH-dependent 7-cyano-7-deazaguanine reductase	1.7.1.13	0.465
3blo	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.464
4m2x	TMQ	Dihydrofolate reductase	1.5.1.3	0.464
4h7z	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	0.461
2zu9	GDP	Mannosyl-3-phosphoglycerate synthase	2.4.1.217	0.458
2ivp	ATP	tRNA N6-adenosine threonylcarbamoyltransferase	/	0.455
1xzq	FON	tRNA modification GTPase MnmE	3.6.5	0.452
3m3z	3F5	Heat shock cognate 71 kDa protein	/	0.452
4ocv	ANP	Aminoglycoside phosphotransferase	/	0.452
1pxg	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.451
1it7	GUN	tRNA-guanine(15) transglycosylase	2.4.2.48	0.450
2x7g	PVB	SRSF protein kinase 2	2.7.11.1	0.450
4feu	537	Aminoglycoside 3'-phosphotransferase AphA1-IAB	/	0.450
2zsc	BTN	Tamavidin2	/	0.447
1efy	BZC	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.446
3gc5	2MQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.446
4l17	DNQ	Glutamate receptor 2	/	0.445
1dg7	WRB	Dihydrofolate reductase	1.5.1.3	0.444
3bt9	DEQ	HTH-type transcriptional regulator QacR	/	0.444
3coy	53H	Pantothenate synthetase	6.3.2.1	0.444
3cqw	CQW	RAC-alpha serine/threonine-protein kinase	2.7.11.1	0.444
2j2p	SC2	Ficolin-2	/	0.443
3abx	RCB	Glucanase	/	0.443
3bll	BPQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.443
1uze	EAL	Angiotensin-converting enzyme	3.2.1	0.442
2itp	AEE	Epidermal growth factor receptor	2.7.10.1	0.442
3cow	52H	Pantothenate synthetase	6.3.2.1	0.442
1x8b	824	Wee1-like protein kinase	2.7.10.2	0.441
2iea	TDP	Pyruvate dehydrogenase E1 component	1.2.4.1	0.441
2qnq	QN3	Gag-Pol polyprotein	3.4.23.16	0.441
3l9m	L9M	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.441
5dn1	AMZ	Phosphoribosyl isomerase A	5.3.1.16	0.441
2gr1	FAD	Ferredoxin reductase	/	0.440
3ex8	AIF	Riboflavin biosynthesis protein RibD	1.1.1.193	0.440