sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 | 1.000 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.604 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.553 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.544 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.537 | |
| 3q9x | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.523 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.510 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.509 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.503 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.491 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.490 | |
| 4dgm | AGI | Casein kinase II subunit alpha | 2.7.11.1 | 0.477 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.475 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.474 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.473 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 1daw | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.459 | |
| 2yaa | ATP | Death-associated protein kinase 2 | / | 0.458 | |
| 2pvm | P29 | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 2fvd | LIA | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3qxp | X64 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.448 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 3mb7 | 14I | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 3amb | VX6 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 |