scPDB - Distribution of Cavity Similarity values of 3p0p entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3p0p	NNF	Tankyrase-2	2.4.2.30

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
3p0p	NNF	Tankyrase-2	2.4.2.30	1.000
4l0i	1UW	Tankyrase-2	2.4.2.30	0.643
4iue	AJ4	Tankyrase-2	2.4.2.30	0.620
4l33	F70	Tankyrase-2	2.4.2.30	0.617
4hlf	15Z	Tankyrase-2	2.4.2.30	0.616
4bue	JQF	Tankyrase-2	2.4.2.30	0.611
4l32	1VF	Tankyrase-2	2.4.2.30	0.609
4bux	F35	Tankyrase-2	2.4.2.30	0.604
4bus	32F	Tankyrase-2	2.4.2.30	0.599
4l0t	1V0	Tankyrase-2	2.4.2.30	0.598
4l0v	1V1	Tankyrase-2	2.4.2.30	0.596
4hlh	20D	Tankyrase-2	2.4.2.30	0.589
4kzl	20D	Tankyrase-2	2.4.2.30	0.586
4buf	F36	Tankyrase-2	2.4.2.30	0.584
4hl5	15W	Tankyrase-2	2.4.2.30	0.582
4l2f	1V3	Tankyrase-2	2.4.2.30	0.577
4l2g	1V4	Tankyrase-2	2.4.2.30	0.575
4avw	G18	Tankyrase-2	2.4.2.30	0.566
4bs4	A64	Tankyrase-2	2.4.2.30	0.561
4pnr	G18	Tankyrase-2	2.4.2.30	0.561
5aku	29F	Tankyrase-2	2.4.2.30	0.560
4hki	FLN	Tankyrase-2	2.4.2.30	0.557
4hmh	F94	Tankyrase-2	2.4.2.30	0.555
4hlm	16S	Tankyrase-2	2.4.2.30	0.554
4krs	1SX	Tankyrase-1	2.4.2.30	0.554
4l2k	1V8	Tankyrase-2	2.4.2.30	0.553
4j21	AJ6	Tankyrase-2	2.4.2.30	0.548
4hlk	431	Tankyrase-2	2.4.2.30	0.547
4buw	F33	Tankyrase-2	2.4.2.30	0.541
4hkn	LU2	Tankyrase-2	2.4.2.30	0.539
4tkg	09L	Tankyrase-2	2.4.2.30	0.521
4bj9	UHB	Tankyrase-2	2.4.2.30	0.516
4hyf	1AK	Tankyrase-2	2.4.2.30	0.506
4pnm	NU1	Tankyrase-2	2.4.2.30	0.504
4msk	2C8	Tankyrase-1	2.4.2.30	0.496
4l09	1UR	Tankyrase-2	2.4.2.30	0.491
4bjb	P34	Tankyrase-2	2.4.2.30	0.487
4j3l	AJ5	Tankyrase-2	2.4.2.30	0.480
4tjy	3GN	Tankyrase-2	2.4.2.30	0.477
4i9i	1DY	Tankyrase-1	2.4.2.30	0.471
4li6	1XO	Tankyrase-1	2.4.2.30	0.467
1efy	BZC	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.466
3rsv	3RS	Beta-secretase 1	3.4.23.46	0.466
3l3m	A92	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.461
2bf7	HBI	Pteridine reductase 1	1.5.1.33	0.460
3aiv	HBO	4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic	3.2.1.182	0.460
2bfa	CB3	Pteridine reductase 1	1.5.1.33	0.459
4k4e	K4E	Tankyrase-1	2.4.2.30	0.459
3qpn	PFK	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.454
1pax	DHQ	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.451
3qpo	PFR	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.449
4fcb	0T7	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.447
2dw4	FAD	Lysine-specific histone demethylase 1A	1	0.446
4buv	16I	Tankyrase-2	2.4.2.30	0.445
4fcd	0T6	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.444
3gn7	3GN	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.442
3qpp	PFW	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.442
4phl	PIL	Phosphodiesterase	/	0.441
4avu	LDR	Tankyrase-2	2.4.2.30	0.440