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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3ef6FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component1.18.1.3

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3ef6FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component1.18.1.31.000
4emjFADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component1.18.1.30.511
2gr3FADFerredoxin reductase/0.495
5fs6FADApoptosis-inducing factor 1, mitochondrial1.1.10.471
4h4sFADBiphenyl dioxygenase ferredoxin reductase subunit/0.468
4h4pFADBiphenyl dioxygenase ferredoxin reductase subunit/0.465
3gd3FADApoptosis-inducing factor 1, mitochondrial1.1.10.445
1gv4FADApoptosis-inducing factor 1, mitochondrial1.1.10.444
3lb8FADPutidaredoxin reductase1.18.1.50.443
4h4vFADBiphenyl dioxygenase ferredoxin reductase subunit/0.443
5fs8FADApoptosis-inducing factor 1, mitochondrial1.1.10.440