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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3e33ED7Protein farnesyltransferase subunit beta2.5.1.58

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3e33ED7Protein farnesyltransferase subunit beta2.5.1.581.000
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.719
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.670
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.659
1s63778Protein farnesyltransferase subunit beta2.5.1.580.656
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.636
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.632
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.626
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.624
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.624
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.622
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.622
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.617
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.610
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.593
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.591
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.567
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.560
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.542
4gto7TOProtein farnesyltransferase subunit beta2.5.1.580.520
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.511
3q7fED2Uncharacterized protein/0.505
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.498
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.490
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.490
4gtm7TMProtein farnesyltransferase subunit beta2.5.1.580.485
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.482
3sfy3FYUncharacterized protein/0.479
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.471
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.465
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.460