Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3e32ED2Protein farnesyltransferase subunit beta2.5.1.58

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3e32ED2Protein farnesyltransferase subunit beta2.5.1.581.000
4gtm7TMProtein farnesyltransferase subunit beta2.5.1.580.664
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.660
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.651
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.646
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.644
1s63778Protein farnesyltransferase subunit beta2.5.1.580.639
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.637
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.635
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.632
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.630
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.621
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.616
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.609
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.603
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.598
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.596
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.596
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.569
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.561
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.543
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.540
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.535
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.531
1n4qLYS_CYS_VAL_ILE_LEUGeranylgeranyl transferase type-1 subunit beta2.5.1.590.529
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.524
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.513
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.504
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.504
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.488
4gto7TOProtein farnesyltransferase subunit beta2.5.1.580.482
3q7fED2Uncharacterized protein/0.481
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.463
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.460
3sfy3FYUncharacterized protein/0.457
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.449