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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.723
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.706
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.703
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.702
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.685
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.677
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.650
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.637
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.628
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.620
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.611
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.608
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.593
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.593
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.592
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.587
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.587
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.586
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.574
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.568
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.567
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.566
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.565
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.561
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.556
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.551
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.549
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.547
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.547
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.546
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.546
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.534
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.532
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.527
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.523
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.518
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.515
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.508
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.503
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.502
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
3cqwCQWRAC-alpha serine/threonine-protein kinase2.7.11.10.482
4yxsEMUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
2uvyGVIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3x2uATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4qnyANPMitogen activated protein kinase, putative/0.442