Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1y91CT9Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1y91CT9Cyclin-dependent kinase 22.7.11.221.000
4ek816KCyclin-dependent kinase 22.7.11.220.576
3s1h56ZCyclin-dependent kinase 22.7.11.220.572
1oirHDYCyclin-dependent kinase 22.7.11.220.569
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.557
3rak03ZCyclin-dependent kinase 22.7.11.220.554
4acm7YGCyclin-dependent kinase 22.7.11.220.548
2xmyCDKCyclin-dependent kinase 22.7.11.220.545
4fkv61KCyclin-dependent kinase 22.7.11.220.543
3rk708ZCyclin-dependent kinase 22.7.11.220.542
3lfnA27Cyclin-dependent kinase 22.7.11.220.541
2r3jSCJCyclin-dependent kinase 22.7.11.220.540
3lfqA28Cyclin-dependent kinase 22.7.11.220.539
2uznC96Cyclin-dependent kinase 22.7.11.220.534
1pxlCK4Cyclin-dependent kinase 22.7.11.220.532
1g5sI17Cyclin-dependent kinase 22.7.11.220.531
2b52D42Cyclin-dependent kinase 22.7.11.220.528
2c6o4SPCyclin-dependent kinase 22.7.11.220.527
1oitHDTCyclin-dependent kinase 22.7.11.220.526
3rmf20ZCyclin-dependent kinase 22.7.11.220.524
3rpv26ZCyclin-dependent kinase 22.7.11.220.523
2a0cCK9Cyclin-dependent kinase 22.7.11.220.520
4fks46KCyclin-dependent kinase 22.7.11.220.519
1pxoCK7Cyclin-dependent kinase 22.7.11.220.517
3r1yX76Cyclin-dependent kinase 22.7.11.220.516
3r8lZ30Cyclin-dependent kinase 22.7.11.220.516
3qtxX43Cyclin-dependent kinase 22.7.11.220.515
3sw418KCyclin-dependent kinase 22.7.11.220.514
3wblPDYCyclin-dependent kinase 22.7.11.220.513
3rjc06ZCyclin-dependent kinase 22.7.11.220.509
1ke5LS1Cyclin-dependent kinase 22.7.11.220.507
3qu0X40Cyclin-dependent kinase 22.7.11.220.507
1ykr628Cyclin-dependent kinase 22.7.11.220.506
2btsU32Cyclin-dependent kinase 22.7.11.220.504
3iggEFQCyclin-dependent kinase 22.7.11.220.503
3rpo24ZCyclin-dependent kinase 22.7.11.220.502
3rk909ZCyclin-dependent kinase 22.7.11.220.501
3rni21ZCyclin-dependent kinase 22.7.11.220.500
1aq1STUCyclin-dependent kinase 22.7.11.220.496
3qzgX67Cyclin-dependent kinase 22.7.11.220.494
3r83Z14Cyclin-dependent kinase 22.7.11.220.494
3qtrX36Cyclin-dependent kinase 22.7.11.220.492
2r3lSCWCyclin-dependent kinase 22.7.11.220.489
2uzoC62Cyclin-dependent kinase 22.7.11.220.489
2vtsLZCCyclin-dependent kinase 22.7.11.220.489
2btrU73Cyclin-dependent kinase 22.7.11.220.488
4fkg4CKCyclin-dependent kinase 22.7.11.220.487
2w1hL0FCyclin-dependent kinase 22.7.11.220.485
1fvv107Cyclin-dependent kinase 22.7.11.220.484
3fz1B98Cyclin-dependent kinase 22.7.11.220.484
2a4lRRCCyclin-dependent kinase 22.7.11.220.483
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.482
3ezrEZRCyclin-dependent kinase 22.7.11.220.482
4ek610KCyclin-dependent kinase 22.7.11.220.482
1w8cN69Cyclin-dependent kinase 22.7.11.220.481
2vtrLZBCyclin-dependent kinase 22.7.11.220.481
3le62BZCyclin-dependent kinase 22.7.11.220.481
3r1sX73Cyclin-dependent kinase 22.7.11.220.481
2b53D23Cyclin-dependent kinase 22.7.11.220.480
2ds11CDCyclin-dependent kinase 22.7.11.220.478
2vttLZDCyclin-dependent kinase 22.7.11.220.478
3r71X86Cyclin-dependent kinase 22.7.11.220.478
1gih1PUCyclin-dependent kinase 22.7.11.220.477
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.477
4fki09KCyclin-dependent kinase 22.7.11.220.477
3qtuX44Cyclin-dependent kinase 22.7.11.220.475
1w0xOLOCyclin-dependent kinase 22.7.11.220.474
1ke6LS2Cyclin-dependent kinase 22.7.11.220.473
2r3kSCQCyclin-dependent kinase 22.7.11.220.473
2vv9IM9Cyclin-dependent kinase 22.7.11.220.472
1b38ATPCyclin-dependent kinase 22.7.11.220.471
1e1xNW1Cyclin-dependent kinase 22.7.11.220.471
1ke7LS3Cyclin-dependent kinase 22.7.11.220.469
1pxmCK5Cyclin-dependent kinase 22.7.11.220.468
2bhhRYUCyclin-dependent kinase 22.7.11.220.468
3sqq99ZCyclin-dependent kinase 22.7.11.220.468
4fkw62KCyclin-dependent kinase 22.7.11.220.468
4bgh3I6Cyclin-dependent kinase 22.7.11.220.467
1hckATPCyclin-dependent kinase 22.7.11.220.465
3ezvEZVCyclin-dependent kinase 22.7.11.220.465
3py0SU9Cyclin-dependent kinase 22.7.11.220.465
1p2a5BNCyclin-dependent kinase 22.7.11.220.464
2c6lDT4Cyclin-dependent kinase 22.7.11.220.464
4fkr45KCyclin-dependent kinase 22.7.11.220.464
1ckpPVBCyclin-dependent kinase 22.7.11.220.463
1gii1PUCyclin-dependent kinase 22.7.11.220.463
1h1r6CPCyclin-dependent kinase 22.7.11.220.463
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.463
3ral04ZCyclin-dependent kinase 22.7.11.220.463
3qwjX6ACyclin-dependent kinase 22.7.11.220.462
3r7yZ04Cyclin-dependent kinase 22.7.11.220.462
3r8pZ46Cyclin-dependent kinase 22.7.11.220.462
4fklCK2Cyclin-dependent kinase 22.7.11.220.462
4fko20KCyclin-dependent kinase 22.7.11.220.462
3s2pPMUCyclin-dependent kinase 22.7.11.220.461
3qqlX03Cyclin-dependent kinase 22.7.11.220.459
1di8DTQCyclin-dependent kinase 22.7.11.220.458
4fkj11KCyclin-dependent kinase 22.7.11.220.458
3r9oZ71Cyclin-dependent kinase 22.7.11.220.457
3sw719KCyclin-dependent kinase 22.7.11.220.455
2vthLZ2Cyclin-dependent kinase 22.7.11.220.454
4fkq42KCyclin-dependent kinase 22.7.11.220.454
2vu3LZECyclin-dependent kinase 22.7.11.220.453
3ddpRC8Cyclin-dependent kinase 22.7.11.220.453
2eufLQQCyclin-dependent kinase 62.7.11.220.451
3sheI85MAP kinase-activated protein kinase 32.7.11.10.451
2vtqLZACyclin-dependent kinase 22.7.11.220.450
3r8vZ62Cyclin-dependent kinase 22.7.11.220.448
3rkb12ZCyclin-dependent kinase 22.7.11.220.448
2x1nX1NCyclin-dependent kinase 22.7.11.220.447
4anmWULCasein kinase II subunit alpha2.7.11.10.447
4nj32KDCyclin-dependent kinase 22.7.11.220.447
1h0w207Cyclin-dependent kinase 22.7.11.220.446
3qtzX42Cyclin-dependent kinase 22.7.11.220.446
4fkt48KCyclin-dependent kinase 22.7.11.220.446
1vjy460TGF-beta receptor type-12.7.11.300.444
4dgnLU2Casein kinase II subunit alpha2.7.11.10.444
1b39ATPCyclin-dependent kinase 22.7.11.220.443
2exmZIPCyclin-dependent kinase 22.7.11.220.443
1ke9LS5Cyclin-dependent kinase 22.7.11.220.442
1y8yCT7Cyclin-dependent kinase 22.7.11.220.442
2c6kDT2Cyclin-dependent kinase 22.7.11.220.442
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.442
3ig7EFPCyclin-dependent kinase 22.7.11.220.440