sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1v2h	GUN	Purine nucleoside phosphorylase	2.4.2.1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1v2h	GUN	Purine nucleoside phosphorylase	2.4.2.1	1.000
1v3q	2DI	Purine nucleoside phosphorylase	2.4.2.1	0.541
1fxu	GU7	Purine nucleoside phosphorylase	2.4.2.1	0.508
1a9p	9DI	Purine nucleoside phosphorylase	2.4.2.1	0.504
1rt9	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.479
2on6	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.476
1yry	MSG	Purine nucleoside phosphorylase	2.4.2.1	0.474
1rr6	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.469
3k8q	22A	Purine nucleoside phosphorylase	2.4.2.1	0.466
1rfg	GMP	Purine nucleoside phosphorylase	2.4.2.1	0.464
1rct	NOS	Purine nucleoside phosphorylase	2.4.2.1	0.444