Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1h51FMNPentaerythritol tetranitrate reductase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1h51FMNPentaerythritol tetranitrate reductase/1.000
1vyrFMNPentaerythritol tetranitrate reductase/0.668
2abbFMNPentaerythritol tetranitrate reductase/0.667
1h50FMNPentaerythritol tetranitrate reductase/0.663
3p62FMNPentaerythritol tetranitrate reductase/0.654
3p8iFMNPentaerythritol tetranitrate reductase/0.634
3p74FMNPentaerythritol tetranitrate reductase/0.624
3p67FMNPentaerythritol tetranitrate reductase/0.621
1h63FMNPentaerythritol tetranitrate reductase/0.618
3f03FMNPentaerythritol tetranitrate reductase/0.605
3p82FMNPentaerythritol tetranitrate reductase/0.599
3p8jFMNPentaerythritol tetranitrate reductase/0.549
4jicFMNGTN Reductase/0.525
1icqFMN12-oxophytodienoate reductase 11.3.1.420.519
3p84FMNPentaerythritol tetranitrate reductase/0.519
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.511
4e2bFMNDehydrogenase/0.504
3atzFMNProstaglandin F2a synthase/0.503
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.502
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.501
4e2dFMNDehydrogenase/0.501
3atyFMNProstaglandin F2a synthase/0.500
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.494
1q45FMN12-oxophytodienoate reductase 31.3.1.420.492
1icsFMN12-oxophytodienoate reductase 11.3.1.420.490
1icpFMN12-oxophytodienoate reductase 11.3.1.420.488
4df2FMNNADPH dehydrogenase/0.488
3gkaFMNN-ethylmaleimide reductase/0.483
1bwlFMNNADPH dehydrogenase 11.6.99.10.482
4rnuFMNNADPH dehydrogenase 11.6.99.10.475
4h6kFMNNADPH dehydrogenase 11.6.99.10.474
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.472
1oyaFMNNADPH dehydrogenase 11.6.99.10.467
1vjiFMN12-oxophytodienoate reductase 11.3.1.420.463
1oycFMNNADPH dehydrogenase 11.6.99.10.460
4g3jVNTLanosterol 14-alpha-demethylase/0.459
4qaiFMNNADPH dehydrogenase/0.459
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.457
1xe55FEPlasmepsin-23.4.23.390.456
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.456
4awsFMNNADH:flavin oxidoreductase Sye1/0.456
1bwkFMNNADPH dehydrogenase 11.6.99.10.455
4tmbFMNOld yellow enzyme/0.453
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
4rnvFMNNADPH dehydrogenase 11.6.99.10.451
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.449
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
3imgBZ2Pantothenate synthetase6.3.2.10.446
1z44FMNNADPH dehydrogenase/0.445
3s1dZIRCytokinin dehydrogenase 11.5.99.120.444
3tjlFMNNADPH dehydrogenase/0.444
4m5pFMNNADPH dehydrogenase/0.444
4r81FMNPredicted NADH dehydrogenase/0.444
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
2hfuMEVMevalonate kinase/0.443
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.442
1bil0IURenin3.4.23.150.441
1fwkADPHomoserine kinase2.7.1.390.441
3imgBZ3Pantothenate synthetase6.3.2.10.441
4q71FADBifunctional protein PutA/0.440