sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4y38 | 0A9 | Endothiapepsin | 3.4.23.22 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4y38 | 0A9 | Endothiapepsin | 3.4.23.22 | 1.000 | |
| 3prs | RIT | Endothiapepsin | 3.4.23.22 | 0.784 | |
| 4yd7 | F5N | Endothiapepsin | 3.4.23.22 | 0.732 | |
| 3pm4 | F5N | Endothiapepsin | 3.4.23.22 | 0.720 | |
| 3psy | RB9 | Endothiapepsin | 3.4.23.22 | 0.714 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.704 | |
| 3pgi | F41 | Endothiapepsin | 3.4.23.22 | 0.703 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.699 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.699 | |
| 4y3q | F02 | Endothiapepsin | 3.4.23.22 | 0.697 | |
| 4zea | IMI | Endothiapepsin | 3.4.23.22 | 0.696 | |
| 2v00 | V15 | Endothiapepsin | 3.4.23.22 | 0.688 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.668 | |
| 1od1 | 0QS | Endothiapepsin | 3.4.23.22 | 0.667 | |
| 4y4j | LNR | Endothiapepsin | 3.4.23.22 | 0.667 | |
| 1gvw | 0EM | Endothiapepsin | 3.4.23.22 | 0.647 | |
| 4y45 | F91 | Endothiapepsin | 3.4.23.22 | 0.646 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.644 | |
| 1e80 | 0GQ | Endothiapepsin | 3.4.23.22 | 0.636 | |
| 3pbz | F02 | Endothiapepsin | 3.4.23.22 | 0.630 | |
| 1ppk | IVV | Penicillopepsin-1 | 3.4.23.20 | 0.628 | |
| 1gvt | 2ZS | Endothiapepsin | 3.4.23.22 | 0.627 | |
| 2jjj | 0QS | Endothiapepsin | 3.4.23.22 | 0.627 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.626 | |
| 2jji | 0QS | Endothiapepsin | 3.4.23.22 | 0.624 | |
| 1e82 | M90 | Endothiapepsin | 3.4.23.22 | 0.619 | |
| 1gvv | 0GM | Endothiapepsin | 3.4.23.22 | 0.612 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.606 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.599 | |
| 3pi0 | F91 | Endothiapepsin | 3.4.23.22 | 0.598 | |
| 3t7p | 7SP | Endothiapepsin | 3.4.23.22 | 0.596 | |
| 4y57 | F63 | Endothiapepsin | 3.4.23.22 | 0.585 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.573 | |
| 2wec | PP5 | Penicillopepsin-1 | 3.4.23.20 | 0.566 | |
| 3pmu | F7L | Endothiapepsin | 3.4.23.22 | 0.564 | |
| 1eag | A70 | Candidapepsin-2 | 3.4.23.24 | 0.562 | |
| 1ppl | 1Z7 | Penicillopepsin-1 | 3.4.23.20 | 0.556 | |
| 3t6i | NC9 | Endothiapepsin | 3.4.23.22 | 0.556 | |
| 1zap | A70 | Candidapepsin-2 | 3.4.23.24 | 0.552 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.551 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.550 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.541 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.510 | |
| 3t6i | NC8 | Endothiapepsin | 3.4.23.22 | 0.488 | |
| 3q70 | RIT | Candidapepsin-2 | 3.4.23.24 | 0.476 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.474 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.473 | |
| 3pll | F06 | Endothiapepsin | 3.4.23.22 | 0.473 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.471 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.468 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.464 | |
| 3t7q | RB4 | Endothiapepsin | 3.4.23.22 | 0.464 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.461 | |
| 2wea | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.461 | |
| 3pb5 | F63 | Endothiapepsin | 3.4.23.22 | 0.461 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.460 | |
| 3pld | F90 | Endothiapepsin | 3.4.23.22 | 0.460 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.456 | |
| 4y3r | F06 | Endothiapepsin | 3.4.23.22 | 0.456 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.455 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.449 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.446 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.442 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.441 |