scPDB - Distribution of Binding site Similarity values of 4pu2 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4pu2	PLU	Aminopeptidase N

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4pu2	PLU	Aminopeptidase N	/	1.000
4k5o	1OT	M1 family aminopeptidase	3.4.11	0.642
3q43	D66	M1 family aminopeptidase	3.4.11	0.602
4xmx	BES	Aminopeptidase N	3.4.11.2	0.580
4jbs	P52	Endoplasmic reticulum aminopeptidase 2	3.4.11	0.551
4k5p	1OS	M1 family aminopeptidase	3.4.11	0.507
2dqm	BES	Aminopeptidase N	3.4.11.2	0.496
3ebi	BEY	M1 family aminopeptidase	3.4.11	0.492
2yd0	BES	Endoplasmic reticulum aminopeptidase 1	3.4.11	0.490
2hpt	BES	Aminopeptidase N	3.4.11.2	0.488
4q4e	BB2	Aminopeptidase N	3.4.11.2	0.485
4an4	DUD	Putative glycosyl transferase	/	0.484
2xq0	BES	Leukotriene A-4 hydrolase homolog	3.3.2.6	0.472
1ygj	RMC	Pyridoxal kinase	2.7.1.35	0.471
3q44	D50	M1 family aminopeptidase	3.4.11	0.470
1h60	STR	Pentaerythritol tetranitrate reductase	/	0.464
2xlr	FAD	Putative flavin-containing monooxygenase	/	0.461
4bfv	ZVV	Pantothenate kinase	2.7.1.33	0.459
2xfy	ACX	Beta-amylase	3.2.1.2	0.458
3dys	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.456
3dyl	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.454
4bca	FAD	Alkyldihydroxyacetonephosphate synthase, peroxisomal	2.5.1.26	0.454
1pag	FMP	Antiviral protein I	3.2.2.22	0.452
1cjt	FOK	Adenylate cyclase type 2	/	0.450
1cjt	FOK	Adenylate cyclase type 5	/	0.450
2oci	TYC	Valacyclovir hydrolase	3.1	0.450
4phl	PIL	Phosphodiesterase	/	0.450
1wua	AP8	Actin, alpha skeletal muscle	/	0.449
1xl8	152	Peroxisomal carnitine O-octanoyltransferase	2.3.1.137	0.449
2g1n	1IG	Renin	3.4.23.15	0.449
4f7i	NAD	3-isopropylmalate dehydrogenase	1.1.1.85	0.449
4s1i	PLP	Pyridoxal kinase, putative	/	0.449
1c3x	8IG	Purine nucleoside phosphorylase	2.4.2.1	0.448
3fhx	PXL	Pyridoxal kinase	2.7.1.35	0.448
3pe2	E1B	Casein kinase II subunit alpha	2.7.11.1	0.447
4c4o	NAD	SADH	/	0.447
4pjk	ADP	Myosin-2 heavy chain	/	0.447
3dhc	CYK	N-acyl homoserine lactonase AiiA	3.1.1.81	0.446
2hyd	ADP	Putative multidrug export ATP-binding/permease protein SAV1866	3.6.3	0.445
2yy2	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.444
3eku	CY9	Actin-5C	/	0.444
3qiz	QI2	Botulinum neurotoxin type A	3.4.24.69	0.444
1dhr	NAD	Dihydropteridine reductase	1.5.1.34	0.442
2g5w	8PG	12-oxophytodienoate reductase 3	1.3.1.42	0.442
3h3t	16H	Collagen type IV alpha-3-binding protein	/	0.442
1r5g	AO1	Methionine aminopeptidase 2	/	0.441
2bt4	CA2	3-dehydroquinate dehydratase	4.2.1.10	0.441
2c29	NAP	Dihydroflavonol 4-reductase	/	0.441
3ioc	A5D	Pantothenate synthetase	6.3.2.1	0.441
4gh6	LUO	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.441
4hxy	NDP	Plm1	/	0.441
4z63	ILE_THR_GLN_TYS_TYS	Phytosulfokine receptor 1	2.7.11.1	0.441
1h61	PDN	Pentaerythritol tetranitrate reductase	/	0.440
2xtn	GTP	GTPase IMAP family member 2	/	0.440