Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4prvADPDNA gyrase subunit B

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4prvADPDNA gyrase subunit B/1.000
4wucANPDNA gyrase subunit B/0.636
4prxADPDNA gyrase subunit B/0.605
4wudANPDNA gyrase subunit B/0.598
3gw9VNILanosterol 14-alpha-demethylase/0.485
2w06FRVCyclin-dependent kinase 22.7.11.220.475
1nhhANPDNA mismatch repair protein MutL/0.473
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.470
3f3sNADLambda-crystallin homolog/0.465
2po7CHDFerrochelatase, mitochondrial4.99.1.10.464
4mv8ACPBiotin carboxylase6.3.4.140.464
4g3jVNTLanosterol 14-alpha-demethylase/0.463
1fm4DXCMajor pollen allergen Bet v 1-L/0.461
5a3bAPRSIR2 family protein/0.460
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.459
4ambDUDPutative glycosyl transferase/0.458
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.456
2gjlFMNNitronate monooxygenase1.13.12.160.456
2rcyNAPPyrroline-5-carboxylate reductase/0.456
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1xddAAYIntegrin alpha-L/0.455
2ek7SAHDiphthine synthase/0.455
3sdi3SDProteasome subunit beta type-53.4.25.10.455
3sdi3SDProteasome subunit beta type-63.4.25.10.455
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.453
2emuSAHDiphthine synthase/0.449
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.448
2q5g1FAPeroxisome proliferator-activated receptor delta/0.448
2eglSAHDiphthine synthase/0.447
2pb6SAHDiphthine synthase/0.447
4g7gVFVLanosterol 14-alpha-demethylase/0.447
2dxvSAHDiphthine synthase/0.446
2h55DZ8Heat shock protein HSP 90-alpha/0.445
2xlrFADPutative flavin-containing monooxygenase/0.444
3s1dZIRCytokinin dehydrogenase 11.5.99.120.444
3clrFADElectron transfer flavoprotein subunit alpha/0.443
1i59ANPChemotaxis protein CheA2.7.13.30.442
2dsgSAHDiphthine synthase/0.442
2ek2SAHDiphthine synthase/0.442
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.441
2e16SAHDiphthine synthase/0.441
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.441
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
2a94AP0L-lactate dehydrogenase1.1.1.270.440
2d1cNAPIsocitrate dehydrogenase [NADP]1.1.1.420.440
2e8sSAHDiphthine synthase/0.440
3qlsNDPDihydrofolate reductase1.5.1.30.440
4mv1ADPBiotin carboxylase6.3.4.140.440