sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4o4i | GTP | Tubulin alpha-1B chain |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4o4i | GTP | Tubulin alpha-1B chain | / | 1.000 | |
| 4tv9 | GTP | Tubulin alpha-1B chain | / | 0.730 | |
| 5la6 | GTP | Tubulin alpha-1B chain | / | 0.697 | |
| 4wbn | GTP | Tubulin alpha-1B chain | / | 0.687 | |
| 4tuy | GTP | Tubulin alpha-1B chain | / | 0.651 | |
| 4ihj | GTP | Tubulin alpha-1B chain | / | 0.617 | |
| 4iij | GTP | Tubulin alpha-1B chain | / | 0.615 | |
| 3ryh | GTP | Tubulin alpha chain | / | 0.608 | |
| 5jqg | GTP | Tubulin alpha-1B chain | / | 0.607 | |
| 4zol | GTP | Tubulin alpha-1B chain | / | 0.598 | |
| 4o4l | GTP | Tubulin alpha-1B chain | / | 0.569 | |
| 4ffb | GTP | Tubulin alpha-1 chain | / | 0.558 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.492 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.478 | |
| 2o12 | FMN | Chorismate synthase | / | 0.477 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.460 | |
| 4b45 | GSP | Tubulin-like protein CetZ2 | / | 0.456 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.455 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.455 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.451 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.451 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.448 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.448 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.447 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.446 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.446 | |
| 4f6r | GDP | Tubulin beta chain | / | 0.445 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.444 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.443 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.442 | |
| 1qf4 | RPD | Adenylosuccinate synthetase | / | 0.441 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.440 |