scPDB - Distribution of Binding site Similarity values of 4l6g entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4l6g	CNL	1,8-cineole 2-endo-monooxygenase	1.14.13.156

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4l6g	CNL	1,8-cineole 2-endo-monooxygenase	1.14.13.156	1.000
4lht	CNL	1,8-cineole 2-endo-monooxygenase	1.14.13.156	0.867
1t2b	CNL	1,8-cineole 2-endo-monooxygenase	1.14.13.156	0.659
3fwj	CAM	Camphor 5-monooxygenase	1.14.15.1	0.519
4cp4	CAM	Camphor 5-monooxygenase	1.14.15.1	0.509
1iwj	CAM	Camphor 5-monooxygenase	1.14.15.1	0.504
2zax	CAM	Camphor 5-monooxygenase	1.14.15.1	0.504
1yrc	CAM	Camphor 5-monooxygenase	1.14.15.1	0.502
4jx1	CAH	Camphor 5-monooxygenase	1.14.15.1	0.499
3fwf	CAM	Camphor 5-monooxygenase	1.14.15.1	0.497
2zaw	CAM	Camphor 5-monooxygenase	1.14.15.1	0.494
3fwg	CAM	Camphor 5-monooxygenase	1.14.15.1	0.493
2cpp	CAM	Camphor 5-monooxygenase	1.14.15.1	0.492
1t87	CAM	Camphor 5-monooxygenase	1.14.15.1	0.491
4r21	STR	Cytochrome P450 family 17 polypeptide 2	/	0.491
4tuv	CPZ	Cytochrome P450 119	1.14	0.491
2zui	CAM	Camphor 5-monooxygenase	1.14.15.1	0.490
3l63	CAM	Camphor 5-monooxygenase	1.14.15.1	0.490
4nky	3QZ	Steroid 17-alpha-hydroxylase/17,20 lyase	/	0.490
6cp4	CAM	Camphor 5-monooxygenase	1.14.15.1	0.490
2a1n	CAM	Camphor 5-monooxygenase	1.14.15.1	0.489
4kky	CAM	Camphor 5-monooxygenase	1.14.15.1	0.489
2qbo	CAM	Camphor 5-monooxygenase	1.14.15.1	0.488
3gw9	VNI	Lanosterol 14-alpha-demethylase	/	0.487
1noo	CAH	Camphor 5-monooxygenase	1.14.15.1	0.484
2cf6	NAP	Cinnamyl alcohol dehydrogenase 5	1.1.1.195	0.483
1geb	CAM	Camphor 5-monooxygenase	1.14.15.1	0.482
3h4l	ANP	DNA mismatch repair protein PMS1	/	0.482
4l4a	CAM	Camphor 5-monooxygenase	1.14.15.1	0.480
4l4e	CAM	Camphor 5-monooxygenase	1.14.15.1	0.480
4r20	AER	Cytochrome P450 family 17 polypeptide 2	/	0.480
1zmc	NAD	Dihydrolipoyl dehydrogenase, mitochondrial	1.8.1.4	0.479
2w0b	CMW	Lanosterol 14-alpha demethylase	1.14.13.70	0.479
4b7d	QLE	Cytochrome P450 monooxygenase PikC	/	0.478
3cpp	CAM	Camphor 5-monooxygenase	1.14.15.1	0.477
3p62	FMN	Pentaerythritol tetranitrate reductase	/	0.477
2feu	CAM	Camphor 5-monooxygenase	1.14.15.1	0.476
2qbm	CAM	Camphor 5-monooxygenase	1.14.15.1	0.476
3wrl	CAM	Camphor 5-monooxygenase	1.14.15.1	0.476
4lxj	LAN	Lanosterol 14-alpha demethylase	1.14.13.70	0.475
1h51	FMN	Pentaerythritol tetranitrate reductase	/	0.474
3lxi	CAM	Cytochrome P450	/	0.474
3w6h	AZM	Carbonic anhydrase 1	4.2.1.1	0.474
1xe6	5FP	Plasmepsin-2	3.4.23.39	0.473
2a1m	CAM	Camphor 5-monooxygenase	1.14.15.1	0.471
4nkv	AER	Steroid 17-alpha-hydroxylase/17,20 lyase	/	0.471
2vwq	NAP	Glucose 1-dehydrogenase	/	0.469
2vn0	TDZ	Cytochrome P450 2C8	/	0.468
2x0i	NAI	Malate dehydrogenase	/	0.468
1kbq	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.467
1x8v	ESL	Lanosterol 14-alpha demethylase	1.14.13.70	0.467
2ktd	PUC	Prostaglandin-H2 D-isomerase	5.3.99.2	0.467
3zuy	TCH	Transporter	/	0.466
1dz4	CAM	Camphor 5-monooxygenase	1.14.15.1	0.465
3wrh	CAM	Camphor 5-monooxygenase	1.14.15.1	0.465
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.464
4n6h	EJ4	Delta-type opioid receptor	/	0.464
3t3q	9PL	Cytochrome P450 2A6	1.14.13	0.463
3ras	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase	/	0.462
4ek1	CAM	Camphor 5-monooxygenase	1.14.15.1	0.462
2hdh	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.461
3p3z	P3Z	Putative cytochrome P450	/	0.460
1t2c	NAI	L-lactate dehydrogenase	1.1.1.27	0.459
2iya	ZIO	Oleandomycin glycosyltransferase	/	0.459
2rkv	ZBA	Trichothecene 3-O-acetyltransferase	/	0.458
4nmd	FDA	Bifunctional protein PutA	/	0.458
1xe5	5FE	Plasmepsin-2	3.4.23.39	0.457
2y4g	TIR	TamL	/	0.457
3d4p	NAD	L-lactate dehydrogenase 1	1.1.1.27	0.457
1h66	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.456
2qd3	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.456
1vyr	FMN	Pentaerythritol tetranitrate reductase	/	0.455
3cty	FAD	Probable thioredoxin reductase	/	0.454
4yao	FMN	NADPH--cytochrome P450 reductase	/	0.454
2po7	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.453
3gwf	NAP	Cyclohexanone monooxygenase	/	0.453
3p6o	ETG	Camphor 5-monooxygenase	1.14.15.1	0.453
3p99	LNP	Lanosterol 14-alpha-demethylase	/	0.453
3h3r	14H	Collagen type IV alpha-3-binding protein	/	0.452
1bdm	NAX	Malate dehydrogenase	/	0.451
1gpd	NAD	Glyceraldehyde-3-phosphate dehydrogenase	1.2.1.12	0.451
2ca0	PXI	Cytochrome P450 monooxygenase PikC	/	0.451
3t2z	FAD	Sulfide-quinone reductase	/	0.451
4m83	ERY	Oleandomycin glycosyltransferase	2.4.1	0.451
4oqy	NDP	(S)-imine reductase	/	0.451
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.450
1fmj	RTL	Retinol dehydratase	/	0.450
2y3r	TRK	TamL	/	0.450
3ssn	MVI	Mycinamicin VI 2''-O-methyltransferase	/	0.450
4bqp	NAD	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.450
1o9b	NAI	Quinate/shikimate dehydrogenase	/	0.449
3d8v	UD1	Bifunctional protein GlmU	/	0.449
3nr4	PYV	Abscisic acid receptor PYL2	/	0.449
1rv1	IMZ	E3 ubiquitin-protein ligase Mdm2	6.3.2	0.448
1vi2	NAD	Quinate/shikimate dehydrogenase	/	0.448
2h9i	EAD	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.448
2y3s	TIR	TamL	/	0.448
2yej	ZZ3	Heat shock protein HSP 90-alpha	/	0.448
3r6s	CMP	CRP-like cAMP-activated global transcriptional regulator	/	0.448
3uyl	TYD	Probable NDP-rhamnosyltransferase	/	0.448
4fw8	NAI	3-oxoacyl-(Acyl-carrier-protein) reductase	/	0.448
4ktl	1CQ	Cytochrome P450	/	0.448
4v2g	ITC	Tetracycline repressor protein class D	/	0.448
4yaw	2AM	NADPH--cytochrome P450 reductase	/	0.448
2aa3	AP0	L-lactate dehydrogenase	/	0.447
3gob	HXX	DdmC	/	0.447
3hdh	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.447
1f17	NAI	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.446
1llq	NAD	NAD-dependent malic enzyme, mitochondrial	1.1.1.38	0.446
2a94	AP0	L-lactate dehydrogenase	1.1.1.27	0.446
3u9e	COA	Lmo1369 protein	/	0.446
3uic	NAD	Enoyl-[acyl-carrier-protein] reductase [NADH]	/	0.446
5cms	APR	O-acetyl-ADP-ribose deacetylase	/	0.446
1lsj	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.445
2mwg	FMN	Blue-light photoreceptor	/	0.445
4dre	NAI	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.445
4ejm	NAP	Putative zinc-binding dehydrogenase	/	0.445
2nnh	REA	Cytochrome P450 2C8	/	0.444
3nmp	PYV	Abscisic acid receptor PYL2	/	0.444
3oew	NAD	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.444
3oey	NAD	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.444
1h50	FMN	Pentaerythritol tetranitrate reductase	/	0.443
1o0s	NAI	NAD-dependent malic enzyme, mitochondrial	1.1.1.38	0.443
2fy4	COA	Choline O-acetyltransferase	2.3.1.6	0.443
3h3f	NAI	L-lactate dehydrogenase A chain	1.1.1.27	0.443
2ejv	NAD	L-threonine 3-dehydrogenase	/	0.442
2rqf	JH3	Hemolymph juvenile hormone binding protein	/	0.442
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.442
3h3c	P1E	Protein-tyrosine kinase 2-beta	2.7.10.2	0.442
3zky	WT4	Isopenicillin N synthase	1.21.3.1	0.442
4k6f	NAP	Putative Acetoacetyl-CoA reductase	/	0.442
4y8w	STR	Steroid 21-hydroxylase	/	0.442
1guy	NAD	Malate dehydrogenase	/	0.441
2abb	FMN	Pentaerythritol tetranitrate reductase	/	0.441
2y1o	T26	UDP-N-acetylmuramoylalanine--D-glutamate ligase	6.3.2.9	0.441
2y60	M8F	Isopenicillin N synthase	1.21.3.1	0.441
3wyc	NAP	Meso-diaminopimelate D-dehydrogenase	1.4.1.16	0.441
4iaw	LIZ	Neutrophil gelatinase-associated lipocalin	/	0.441
4imo	PWZ	Prostaglandin-H2 D-isomerase	5.3.99.2	0.441
4o3m	ADP	Bloom syndrome protein	3.6.4.12	0.441
3atz	FMN	Prostaglandin F2a synthase	/	0.440
3bc3	OPT	Cathepsin L1	3.4.22.15	0.440