sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 1.000 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.749 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.650 | |
| 4da0 | GNG | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.607 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.587 | |
| 1pr0 | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.585 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.584 | |
| 1pr6 | XYA | Purine nucleoside phosphorylase DeoD-type | / | 0.576 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.575 | |
| 1pke | 2FD | Purine nucleoside phosphorylase DeoD-type | / | 0.565 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.565 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.559 | |
| 1pk9 | 2FA | Purine nucleoside phosphorylase DeoD-type | / | 0.553 | |
| 1a69 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.549 | |
| 1pr1 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.537 | |
| 3uaw | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.534 | |
| 1pr5 | TBN | Purine nucleoside phosphorylase DeoD-type | / | 0.531 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.531 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.526 | |
| 4ts9 | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.515 | |
| 2isc | 223 | Purine nucleoside phosphorylase, putative | / | 0.511 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.505 | |
| 2bsx | NOS | Purine nucleoside phosphorylase | / | 0.504 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.498 | |
| 2i4t | UA2 | Purine nucleoside phosphorylase, putative | / | 0.493 | |
| 3of3 | DIH | Purine nucleoside phosphorylase DeoD-type 1 | / | 0.484 | |
| 5dp2 | NAP | CurF | / | 0.481 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.477 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.469 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.468 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.463 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.462 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.459 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.457 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.456 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.456 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.452 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.450 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.450 | |
| 1k9s | FM2 | Purine nucleoside phosphorylase DeoD-type | / | 0.449 | |
| 4tti | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.449 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.448 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.445 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.445 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.444 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.443 | |
| 1c7o | PPG | Hemolysin | / | 0.441 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.441 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.440 |