sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4b4b | GJB | Glucose-1-phosphate thymidylyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4b4b | GJB | Glucose-1-phosphate thymidylyltransferase | / | 1.000 | |
| 4b5b | BBE | Glucose-1-phosphate thymidylyltransferase | / | 0.663 | |
| 4b4g | KKT | Glucose-1-phosphate thymidylyltransferase | / | 0.643 | |
| 4b42 | 942 | Glucose-1-phosphate thymidylyltransferase | / | 0.632 | |
| 4b2w | BZ0 | Glucose-1-phosphate thymidylyltransferase | / | 0.604 | |
| 4asj | N6A | Glucose-1-phosphate thymidylyltransferase | / | 0.581 | |
| 4asy | N5Y | Glucose-1-phosphate thymidylyltransferase | / | 0.493 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.471 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.467 | |
| 1eio | GCH | Gastrotropin | / | 0.465 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 1fml | RTL | Retinol dehydratase | / | 0.453 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.451 | |
| 2y37 | A54 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.450 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.449 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.448 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.447 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.442 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.440 |