Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3kzoAN0N-acetylornithine carbamoyltransferase2.1.3.9

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3kzoAN0N-acetylornithine carbamoyltransferase2.1.3.91.000
3l04SN0N-acetylornithine carbamoyltransferase2.1.3.90.745
3l06SN0N-acetylornithine carbamoyltransferase2.1.3.90.717
3l05SN0N-acetylornithine carbamoyltransferase2.1.3.90.677
3m4nPA9N-acetylornithine carbamoyltransferase2.1.3.90.547
4lb2DM5Serum albumin/0.489
3ba6AN2Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.486
3dntATPSerine/threonine-protein kinase toxin HipA/0.477
2rd2QSIGlutamine--tRNA ligase6.1.1.180.475
3zkyWT4Isopenicillin N synthase1.21.3.10.470
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.468
1b2lNDCAlcohol dehydrogenase1.1.1.10.466
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.463
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.462
3bgxTMPThymidylate synthase/0.462
3acw651Dehydrosqualene synthase/0.461
1hfqMOTDihydrofolate reductase1.5.1.30.460
3hl0NADMaleylacetate reductase/0.460
1bk0ACVIsopenicillin N synthase1.21.3.10.458
1icvFMNOxygen-insensitive NAD(P)H nitroreductase/0.458
3njoPYVAbscisic acid receptor PYR1/0.458
3tfyCOAN-alpha-acetyltransferase 502.3.10.458
3vi7CBDHematopoietic prostaglandin D synthase/0.458
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
3h4vDVPPteridine reductase 11.5.1.330.457
1w1wAGSStructural maintenance of chromosomes protein 1/0.456
4fj1GEN17beta-hydroxysteroid dehydrogenase/0.456
3zoiM2WIsopenicillin N synthase1.21.3.10.455
2x7hPFNProstaglandin reductase 310.454
2y60M8FIsopenicillin N synthase1.21.3.10.454
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.453
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
4jyzATPGlutamine--tRNA ligase6.1.1.180.452
1d3pBT3Prothrombin3.4.21.50.451
1e92HBIPteridine reductase 11.5.1.330.451
1mvsDTMDihydrofolate reductase1.5.1.30.451
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.451
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
4b4w9L9Bifunctional protein FolD/0.450
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.450
4fhd0TTSpore photoproduct lyase/0.450
1qjfACSIsopenicillin N synthase1.21.3.10.449
1zg32HIIsoflavone 4'-O-methyltransferase/0.449
3rgaILDEpoxide hydrolase LasB5.5.10.449
3rviRVIBeta-secretase 13.4.23.460.449
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.449
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.449
1kl2FONSerine hydroxymethyltransferase/0.448
1kquBR4Phospholipase A2, membrane associated/0.448
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.448
2bf7HBIPteridine reductase 11.5.1.330.448
2bfaCB3Pteridine reductase 11.5.1.330.448
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.448
4bb3KKAIsopenicillin N synthase1.21.3.10.448
4ea2RWZDehydrosqualene synthase/0.448
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.448
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.447
1blzACVIsopenicillin N synthase1.21.3.10.446
1qrtATPGlutamine--tRNA ligase6.1.1.180.446
2gv8NDPThiol-specific monooxygenase1.14.130.446
3qm4PN0Cytochrome P450 2D6/0.446
1gj5130Prothrombin3.4.21.50.445
2jb4A14Isopenicillin N synthase1.21.3.10.445
2r86ATP5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase/0.445
3x21FMNOxygen-insensitive NAD(P)H nitroreductase/0.445
4f6xZYLDehydrosqualene synthase/0.445
1hfpMOTDihydrofolate reductase1.5.1.30.444
1lkeDOGBilin-binding protein/0.444
3vf60H6Glucokinase2.7.1.20.444
2iviACWIsopenicillin N synthase1.21.3.10.443
3ufl508Beta-secretase 13.4.23.460.443
3zg6APRNAD-dependent protein deacetylase sirtuin-63.5.10.443
4a6rTA8Probable aminotransferase/0.443
4bewACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.443
4i1nFOLDihydrofolate reductase1.5.1.30.443
2cn0F25Prothrombin3.4.21.50.442
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
2vcmM11Isopenicillin N synthase1.21.3.10.442
3ge6FMNNitroreductase/0.442
3gncQQQGlutaryl-CoA dehydrogenase/0.442
3keqNADRedox-sensing transcriptional repressor Rex/0.442
3lfcZ86Mitogen-activated protein kinase 14/0.442
4esoNAPPutative oxidoreductase/0.442
4jxzATPGlutamine--tRNA ligase6.1.1.180.442
5ez4NADBetaine-aldehyde dehydrogenase/0.442
1kh3ANPArgininosuccinate synthase/0.441
2d3aADPGlutamine synthetase root isozyme 36.3.1.20.441
2getCOKPantothenate kinase2.7.1.330.441
2iyaZIOOleandomycin glycosyltransferase/0.441
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.441
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.440
1u1d181Uridine phosphorylase2.4.2.30.440
3bl7DD1m7GpppX diphosphatase3.6.1.590.440
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.440
4cthRDFNeprilysin/0.440
4f6vZYMDehydrosqualene synthase/0.440
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440