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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/1.000
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.732
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.571
1o9bNAIQuinate/shikimate dehydrogenase/0.499
4yaw2AMNADPH--cytochrome P450 reductase/0.498
2hk9NAPShikimate dehydrogenase (NADP(+))/0.495
1vi2NADQuinate/shikimate dehydrogenase/0.492
2cy0NAPShikimate dehydrogenase (NADP(+))/0.485
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.477
2ev9NAPShikimate dehydrogenase (NADP(+))/0.473
3t4eNADQuinate/shikimate dehydrogenase/0.469
3gobHXXDdmC/0.464
1ove358Mitogen-activated protein kinase 14/0.462
4q71FADBifunctional protein PutA/0.457
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.456
3h1vTK1Glucokinase2.7.1.20.456
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1nvtNAPShikimate dehydrogenase (NADP(+))/0.455
1synF89Thymidylate synthase/0.453
3fhxPXLPyridoxal kinase2.7.1.350.453
1nytNAPShikimate dehydrogenase (NADP(+))/0.451
3h3sH15Collagen type IV alpha-3-binding protein/0.451
4y9uNAPNADPH--cytochrome P450 reductase/0.451
3pqbVGPPutative oxidoreductase/0.450
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.450
4y9rNAPNADPH--cytochrome P450 reductase/0.450
3bgxMEFThymidylate synthase/0.449
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.448
3gwfNAPCyclohexanone monooxygenase/0.448
3phiNDPShikimate dehydrogenase (NADP(+))/0.448
3tozNADShikimate dehydrogenase (NADP(+))/0.448
1zzrDP9Nitric oxide synthase, brain1.14.13.390.447
2eixFADNADH-cytochrome b5 reductase/0.446
4q73FADBifunctional protein PutA/0.446
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.445
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.444
3to3ATPPetrobactin biosynthesis protein AsbB/0.444
4mleVO1Glucokinase2.7.1.20.444
4y7cNAPNADPH--cytochrome P450 reductase/0.444
4yal2AMNADPH--cytochrome P450 reductase/0.444
4jqh1MFAlr2278 protein/0.443
1amoNAPNADPH--cytochrome P450 reductase/0.442
1zg32HIIsoflavone 4'-O-methyltransferase/0.442
3p99LNPLanosterol 14-alpha-demethylase/0.442
1pkfEPDEpothilone C/D epoxidase1.140.441
1u3dFADCryptochrome-1/0.441
1xddAAYIntegrin alpha-L/0.441
2jn3JN3Fatty acid-binding protein, liver/0.441
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.441
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.441
4g3jVNTLanosterol 14-alpha-demethylase/0.440