sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3fro | NHF | GlgA glycogen synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3fro | NHF | GlgA glycogen synthase | / | 1.000 | |
| 2r4t | ADP | Glycogen synthase | 2.4.1.21 | 0.478 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.469 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 2r4u | ADP | Glycogen synthase | 2.4.1.21 | 0.464 | |
| 3cop | ADP | Glycogen synthase | 2.4.1.21 | 0.463 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.460 | |
| 4o3m | ADP | Bloom syndrome protein | 3.6.4.12 | 0.458 | |
| 4ztv | TA7 | Anthranilate phosphoribosyltransferase | / | 0.457 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.456 | |
| 4z17 | PEP | Enolase | / | 0.456 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.455 | |
| 1mqe | APR | MutT/nudix family protein | / | 0.454 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.452 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.451 | |
| 3uu1 | 14B | Anthranilate phosphoribosyltransferase | / | 0.450 | |
| 3r9i | ADP | Septum site-determining protein MinD | / | 0.447 | |
| 4yqf | GDP | Septin-9 | / | 0.446 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.445 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.445 | |
| 4kq2 | 1S3 | Glycogen [starch] synthase isoform 2 | 2.4.1.11 | 0.445 | |
| 1mk1 | APR | MutT/nudix family protein | / | 0.444 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.443 | |
| 2pz8 | APC | NH(3)-dependent NAD(+) synthetase | / | 0.443 | |
| 3n8n | N88 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.443 | |
| 3vgl | ANP | Glucokinase | / | 0.443 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.442 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 1u28 | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.441 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.441 | |
| 4gpb | GFP | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.441 | |
| 4ike | ADP | Adenylate kinase | / | 0.441 | |
| 4a4z | ANP | Antiviral helicase SKI2 | 3.6.4.13 | 0.440 |