scPDB - Distribution of Binding site Similarity values of 2wxv entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2wxv	WXV	Cyclin-dependent kinase 2	2.7.11.22

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2wxv	WXV	Cyclin-dependent kinase 2	2.7.11.22	1.000
2wih	P48	Cyclin-dependent kinase 2	2.7.11.22	0.656
4fx3	60K	Cyclin-dependent kinase 2	2.7.11.22	0.518
2wpa	889	Cyclin-dependent kinase 2	2.7.11.22	0.517
2wip	P49	Cyclin-dependent kinase 2	2.7.11.22	0.506
2bkz	SBC	Cyclin-dependent kinase 2	2.7.11.22	0.500
3qu0	X40	Cyclin-dependent kinase 2	2.7.11.22	0.496
1vyw	292	Cyclin-dependent kinase 2	2.7.11.22	0.494
2x1n	X1N	Cyclin-dependent kinase 2	2.7.11.22	0.492
3s2p	PMU	Cyclin-dependent kinase 2	2.7.11.22	0.488
1ogu	ST8	Cyclin-dependent kinase 2	2.7.11.22	0.486
1unl	RRC	Cyclin-dependent-like kinase 5	2.7.11.1	0.486
3ral	04Z	Cyclin-dependent kinase 2	2.7.11.22	0.486
3rmf	20Z	Cyclin-dependent kinase 2	2.7.11.22	0.486
4fkv	61K	Cyclin-dependent kinase 2	2.7.11.22	0.483
2i40	BLZ	Cyclin-dependent kinase 2	2.7.11.22	0.482
4fkw	62K	Cyclin-dependent kinase 2	2.7.11.22	0.482
2iw8	4SP	Cyclin-dependent kinase 2	2.7.11.22	0.480
2bhh	RYU	Cyclin-dependent kinase 2	2.7.11.22	0.479
2c6t	DT5	Cyclin-dependent kinase 2	2.7.11.22	0.479
3rni	21Z	Cyclin-dependent kinase 2	2.7.11.22	0.478
4qmy	STU	Serine/threonine-protein kinase 24	2.7.11.1	0.478
4u9a	STU	Interleukin-1 receptor-associated kinase 4	2.7.11.1	0.478
1fvv	107	Cyclin-dependent kinase 2	2.7.11.22	0.477
2vto	LZ8	Cyclin-dependent kinase 2	2.7.11.22	0.477
1gih	1PU	Cyclin-dependent kinase 2	2.7.11.22	0.476
3rak	03Z	Cyclin-dependent kinase 2	2.7.11.22	0.476
1p2a	5BN	Cyclin-dependent kinase 2	2.7.11.22	0.475
2w06	FRV	Cyclin-dependent kinase 2	2.7.11.22	0.475
4fkr	45K	Cyclin-dependent kinase 2	2.7.11.22	0.475
3qqk	X02	Cyclin-dependent kinase 2	2.7.11.22	0.474
3s1h	56Z	Cyclin-dependent kinase 2	2.7.11.22	0.473
3r9h	Z67	Cyclin-dependent kinase 2	2.7.11.22	0.472
1h1s	4SP	Cyclin-dependent kinase 2	2.7.11.22	0.470
1pkd	UCN	Cyclin-dependent kinase 2	2.7.11.22	0.470
2w17	I19	Cyclin-dependent kinase 2	2.7.11.22	0.470
3qqf	X07	Cyclin-dependent kinase 2	2.7.11.22	0.470
3rai	X85	Cyclin-dependent kinase 2	2.7.11.22	0.470
3qxp	X64	Cyclin-dependent kinase 2	2.7.11.22	0.469
3sqq	99Z	Cyclin-dependent kinase 2	2.7.11.22	0.469
2c5n	CK8	Cyclin-dependent kinase 2	2.7.11.22	0.468
4fkt	48K	Cyclin-dependent kinase 2	2.7.11.22	0.468
4fr4	STU	Serine/threonine-protein kinase 32A	2.7.11.1	0.468
1h1r	6CP	Cyclin-dependent kinase 2	2.7.11.22	0.466
3rjc	06Z	Cyclin-dependent kinase 2	2.7.11.22	0.466
1nvr	STU	Serine/threonine-protein kinase Chk1	2.7.11.1	0.465
2cch	ATP	Cyclin-dependent kinase 2	2.7.11.22	0.465
2nry	STU	Interleukin-1 receptor-associated kinase 4	2.7.11.1	0.465
1oir	HDY	Cyclin-dependent kinase 2	2.7.11.22	0.464
3roy	22Z	Cyclin-dependent kinase 2	2.7.11.22	0.464
3tki	S25	Serine/threonine-protein kinase Chk1	2.7.11.1	0.463
4bcn	T9N	Cyclin-dependent kinase 2	2.7.11.22	0.463
3qtq	X35	Cyclin-dependent kinase 2	2.7.11.22	0.462
3rk5	07Z	Cyclin-dependent kinase 2	2.7.11.22	0.462
4qmp	DKI	Serine/threonine-protein kinase 24	2.7.11.1	0.462
3dog	NNN	Cyclin-dependent kinase 2	2.7.11.22	0.461
3qxo	X65	Cyclin-dependent kinase 2	2.7.11.22	0.461
3rk7	08Z	Cyclin-dependent kinase 2	2.7.11.22	0.461
2uzd	C85	Cyclin-dependent kinase 2	2.7.11.22	0.460
2uzl	C94	Cyclin-dependent kinase 2	2.7.11.22	0.460
3bht	MFR	Cyclin-dependent kinase 2	2.7.11.22	0.460
3pj8	404	Cyclin-dependent kinase 2	2.7.11.22	0.460
3rpv	26Z	Cyclin-dependent kinase 2	2.7.11.22	0.460
4bgh	3I6	Cyclin-dependent kinase 2	2.7.11.22	0.460
1pxm	CK5	Cyclin-dependent kinase 2	2.7.11.22	0.459
1aq1	STU	Cyclin-dependent kinase 2	2.7.11.22	0.458
1oiy	N41	Cyclin-dependent kinase 2	2.7.11.22	0.458
4bcp	T3C	Cyclin-dependent kinase 2	2.7.11.22	0.458
4erw	STU	Cyclin-dependent kinase 2	2.7.11.22	0.458
1e9h	INR	Cyclin-dependent kinase 2	2.7.11.22	0.457
1w0x	OLO	Cyclin-dependent kinase 2	2.7.11.22	0.457
2c6i	DT1	Cyclin-dependent kinase 2	2.7.11.22	0.457
2uzb	C75	Cyclin-dependent kinase 2	2.7.11.22	0.457
4kio	G5K	Tyrosine-protein kinase ITK/TSK	2.7.10.2	0.456
2w05	FRT	Cyclin-dependent kinase 2	2.7.11.22	0.455
3qtz	X42	Cyclin-dependent kinase 2	2.7.11.22	0.455
3r9d	X6B	Cyclin-dependent kinase 2	2.7.11.22	0.455
4ft7	H3K	Serine/threonine-protein kinase Chk1	2.7.11.1	0.454
1nvs	UCM	Serine/threonine-protein kinase Chk1	2.7.11.1	0.453
2xnb	Y8L	Cyclin-dependent kinase 2	2.7.11.22	0.453
4acm	7YG	Cyclin-dependent kinase 2	2.7.11.22	0.453
2j9m	PY8	Cyclin-dependent kinase 2	2.7.11.22	0.452
4hyh	1AM	Serine/threonine-protein kinase Chk1	2.7.11.1	0.452
1v1k	3FP	Cyclin-dependent kinase 2	2.7.11.22	0.451
2xck	MH4	3-phosphoinositide-dependent protein kinase 1	2.7.11.1	0.451
1oi9	N20	Cyclin-dependent kinase 2	2.7.11.22	0.450
1y91	CT9	Cyclin-dependent kinase 2	2.7.11.22	0.450
4qo9	627	Serine/threonine-protein kinase 24	2.7.11.1	0.450
1g5s	I17	Cyclin-dependent kinase 2	2.7.11.22	0.448
2r3l	SCW	Cyclin-dependent kinase 2	2.7.11.22	0.448
2uze	C95	Cyclin-dependent kinase 2	2.7.11.22	0.448
3r73	X87	Cyclin-dependent kinase 2	2.7.11.22	0.448
3qtx	X43	Cyclin-dependent kinase 2	2.7.11.22	0.447
4fkq	42K	Cyclin-dependent kinase 2	2.7.11.22	0.447
2r3k	SCQ	Cyclin-dependent kinase 2	2.7.11.22	0.446
2vtp	LZ9	Cyclin-dependent kinase 2	2.7.11.22	0.446
1oit	HDT	Cyclin-dependent kinase 2	2.7.11.22	0.445
2vtn	LZ7	Cyclin-dependent kinase 2	2.7.11.22	0.444
3say	OFT	Glycogen synthase kinase-3 beta	2.7.11.26	0.444
4ek6	10K	Cyclin-dependent kinase 2	2.7.11.22	0.444
3rm7	19Z	Cyclin-dependent kinase 2	2.7.11.22	0.443
4c34	STU	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.443
1ke6	LS2	Cyclin-dependent kinase 2	2.7.11.22	0.442
2uzn	C96	Cyclin-dependent kinase 2	2.7.11.22	0.442
3uli	1N3	Cyclin-dependent kinase 2	2.7.11.22	0.442
4gh2	HK0	Serine/threonine-protein kinase Chk1	2.7.11.1	0.442
3ti1	B49	Cyclin-dependent kinase 2	2.7.11.22	0.441
4ftt	6HK	Serine/threonine-protein kinase Chk1	2.7.11.1	0.441
4qmz	B49	Serine/threonine-protein kinase 24	2.7.11.1	0.441
1nvq	UCN	Serine/threonine-protein kinase Chk1	2.7.11.1	0.440
3lfn	A27	Cyclin-dependent kinase 2	2.7.11.22	0.440
4bgg	844	Activin receptor type-1	2.7.11.30	0.440