sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ngd | ADP | Heat shock cognate 71 kDa protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ngd | ADP | Heat shock cognate 71 kDa protein | / | 1.000 | |
| 3hsc | ADP | Heat shock cognate 71 kDa protein | / | 0.726 | |
| 1ngh | ATP | Heat shock cognate 71 kDa protein | / | 0.707 | |
| 1ngi | ANP | Heat shock cognate 71 kDa protein | / | 0.690 | |
| 1ngb | ADP | Heat shock cognate 71 kDa protein | / | 0.669 | |
| 1atr | ADP | Heat shock cognate 71 kDa protein | / | 0.661 | |
| 1ngc | ADP | Heat shock cognate 71 kDa protein | / | 0.658 | |
| 1nge | ATP | Heat shock cognate 71 kDa protein | / | 0.641 | |
| 1ats | ADP | Heat shock cognate 71 kDa protein | / | 0.625 | |
| 1ngj | ANP | Heat shock cognate 71 kDa protein | / | 0.596 | |
| 2qwn | ADP | Heat shock cognate 71 kDa protein | / | 0.572 | |
| 5aqz | SGV | Heat shock 70 kDa protein 1A | / | 0.558 | |
| 3m3z | 3F5 | Heat shock cognate 71 kDa protein | / | 0.556 | |
| 5f2r | ACP | 78 kDa glucose-regulated protein | / | 0.550 | |
| 2qwl | ADP | Heat shock cognate 71 kDa protein | / | 0.539 | |
| 5f1x | ATP | 78 kDa glucose-regulated protein | / | 0.525 | |
| 3fzm | 3GO | Heat shock cognate 71 kDa protein | / | 0.503 | |
| 3qft | NAP | NADPH--cytochrome P450 reductase | / | 0.488 | |
| 4h5t | ADP | Heat shock cognate 71 kDa protein | / | 0.486 | |
| 3fe1 | ADP | Heat shock 70 kDa protein 6 | / | 0.479 | |
| 3w3d | ATP | Actin, gamma-enteric smooth muscle | / | 0.479 | |
| 3ldo | ANP | 78 kDa glucose-regulated protein | / | 0.475 | |
| 1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.470 | |
| 4y9r | NAP | NADPH--cytochrome P450 reductase | / | 0.463 | |
| 1qz5 | ATP | Actin, alpha skeletal muscle | / | 0.458 | |
| 1nm1 | ATP | Major actin | / | 0.456 | |
| 3nta | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.453 | |
| 4io8 | 3FD | Heat shock 70 kDa protein 1B | / | 0.453 | |
| 4y8v | ADP | Acyl-CoA synthetase (NDP forming) | / | 0.452 | |
| 1ja1 | NAP | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 3qe2 | NAP | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.448 | |
| 1c0f | ATP | Major actin | / | 0.444 | |
| 1j1b | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
| 2bpo | NAP | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 3m1f | ATP | Actin, alpha skeletal muscle | / | 0.444 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4jhd | ANP | Actin-5C | / | 0.444 | |
| 3qfc | NAP | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 3ua8 | 08W | Glutamate receptor 2 | / | 0.442 | |
| 4cbx | ATP | Actin-2 | / | 0.441 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.440 | |
| 3mn9 | ATP | Actin-5C | / | 0.440 |