Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5aku 29F Tankyrase-2 2.4.2.30

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
5aku 29FTankyrase-2 2.4.2.30 0.953
3kr8 XAVTankyrase-2 2.4.2.30 0.888
4bud 29FTankyrase-2 2.4.2.30 0.880
4bu9 08CTankyrase-2 2.4.2.30 0.873
4bue JQFTankyrase-2 2.4.2.30 0.866
4bs4 A64Tankyrase-2 2.4.2.30 0.847
4buu F38Tankyrase-2 2.4.2.30 0.845
4but 31FTankyrase-2 2.4.2.30 0.839
4buf F36Tankyrase-2 2.4.2.30 0.838
4buv 16ITankyrase-2 2.4.2.30 0.835
4bus 32FTankyrase-2 2.4.2.30 0.833
4bui W2ETankyrase-2 2.4.2.30 0.829
4buw F33Tankyrase-2 2.4.2.30 0.829
4bux F35Tankyrase-2 2.4.2.30 0.829
4l10 A63Tankyrase-2 2.4.2.30 0.805
4hlh 20DTankyrase-2 2.4.2.30 0.802
4l0i 1UWTankyrase-2 2.4.2.30 0.801
4l0v 1V1Tankyrase-2 2.4.2.30 0.801
4kzl 20DTankyrase-2 2.4.2.30 0.795
4l0s 1UZTankyrase-2 2.4.2.30 0.788
4l33 F70Tankyrase-2 2.4.2.30 0.787
4hlm 16STankyrase-2 2.4.2.30 0.786
4l0t 1V0Tankyrase-2 2.4.2.30 0.786
4hlk 431Tankyrase-2 2.4.2.30 0.784
4kzu A73Tankyrase-2 2.4.2.30 0.783
4hl5 15WTankyrase-2 2.4.2.30 0.774
4l2k 1V8Tankyrase-2 2.4.2.30 0.770
4hlg 20BTankyrase-2 2.4.2.30 0.765
4l2f 1V3Tankyrase-2 2.4.2.30 0.759
4l32 1VFTankyrase-2 2.4.2.30 0.755
4hkk AGITankyrase-2 2.4.2.30 0.744
4hmh F94Tankyrase-2 2.4.2.30 0.741
4l2g 1V4Tankyrase-2 2.4.2.30 0.733
4avw G18Tankyrase-2 2.4.2.30 0.730
4hkn LU2Tankyrase-2 2.4.2.30 0.712
4avu LDRTankyrase-2 2.4.2.30 0.701
3gn7 3GNPoly [ADP-ribose] polymerase 1 2.4.2.30 0.690
3p0p NNFTankyrase-2 2.4.2.30 0.690
4msk 2C8Tankyrase-1 2.4.2.30 0.690
4pnr G18Tankyrase-2 2.4.2.30 0.690
4gv4 MEJPoly [ADP-ribose] polymerase 3 2.4.2.30 0.688
4gv0 8MEPoly [ADP-ribose] polymerase 3 2.4.2.30 0.687
4pnm NU1Tankyrase-2 2.4.2.30 0.685
3c4h DRLPoly [ADP-ribose] polymerase 3 2.4.2.30 0.684
4tjy 3GNTankyrase-2 2.4.2.30 0.682
4krs 1SXTankyrase-1 2.4.2.30 0.677
4gv7 MEWPoly [ADP-ribose] polymerase 1 2.4.2.30 0.674
4bjc RPBTankyrase-2 2.4.2.30 0.673
4msg 2C6Tankyrase-1 2.4.2.30 0.665
4gv2 5MEPoly [ADP-ribose] polymerase 3 2.4.2.30 0.663
3c49 KU8Poly [ADP-ribose] polymerase 3 2.4.2.30 0.661
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.660
4e5f 0N7Polymerase acidic protein / 0.658
4hhz 15SPoly [ADP-ribose] polymerase 1 2.4.2.30 0.658
3u9y 09LTankyrase-2 2.4.2.30 0.656
5ds3 09LPoly [ADP-ribose] polymerase 1 2.4.2.30 0.655
1pax DHQPoly [ADP-ribose] polymerase 1 2.4.2.30 0.654
2rd6 78PPoly [ADP-ribose] polymerase 1 2.4.2.30 0.654
3l3l L3LPoly [ADP-ribose] polymerase 1 2.4.2.30 0.651