Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4v37 NAD Betaine aldehyde dehydrogenase, chloroplastic 1.2.1.8

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4v37 NADBetaine aldehyde dehydrogenase, chloroplastic 1.2.1.8 1.167
4i8p NADAminoaldehyde dehydrogenase 1 / 1.058
1o04 NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 1.015
4a0m NADBetaine aldehyde dehydrogenase, chloroplastic 1.2.1.8 0.981
4pz2 NADAldehyde dehydrogenase 2-6 / 0.973
1a4z NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.918
2ehu NAD1-pyrroline-5-carboxylate dehydrogenase / 0.909
4i8q NADPutative betaine aldehyde dehyrogenase / 0.907
2j40 NAD1-pyrroline-5-carboxylate dehydrogenase / 0.897
1uxr NAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.877
2j5n NAD1-pyrroline-5-carboxylate dehydrogenase / 0.876
2eii NAD1-pyrroline-5-carboxylate dehydrogenase / 0.874
2bhp NAD1-pyrroline-5-carboxylate dehydrogenase / 0.873
2d4e NAD5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseiheyensis HTE831] / 0.870
2ehq NAP1-pyrroline-5-carboxylate dehydrogenase / 0.866
3efv NADPutative succinate-semialdehyde dehydrogenase / 0.863
3rhl NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.863
4gnz NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.863
3b4w NADAldehyde dehydrogenase family protein / 0.857
2euh NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1.2.1.9 0.852
3rhr NDPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.851
4i1w NAD2-aminomuconate 6-semialdehyde dehydrogenase / 0.847
1uxt NADNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.845
1uxn NAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.838
4oe2 NAD2-aminomuconate 6-semialdehyde dehydrogenase / 0.834
3rhq NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.828
2j6l NAIAlpha-aminoadipic semialdehyde dehydrogenase 1.2.1.31 0.823
2id2 NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1.2.1.9 0.820
3rhj NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.816
2o2q NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.815
2jg7 NADAntiquitin / 0.813
2eit NAD1-pyrroline-5-carboxylate dehydrogenase / 0.808
1t90 NADMalonate-semialdehyde dehydrogenase 1.2.1.27 0.806
1o9j NADAldehyde dehydrogenase, cytosolic 1 1.2.1.3 0.801
1uxv NAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.790
1uxp NAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.785
3v9l NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial 1.2.1.88 0.777
1bpw NADBetaine aldehyde dehydrogenase 1.2.1.8 0.750
1ky8 NAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.737
3haz NADBifunctional protein PutA / 0.732
3lv1 NAPNAD(P)-dependent benzaldehyde dehydrogenase 1.2.1.28 0.729
4pxl NADAldehyde dehydrogenase3 / 0.728
4ihi NADProbable pyrroline-5-carboxylate dehydrogenase RocA / 0.710
4nmj NAPAldehyde dehydrogenase / 0.710
2y5d NAP3,4-dehydroadipyl-CoA semialdehyde dehydrogenase / 0.709
3iwj NADAminoaldehyde dehydrogenase / 0.703
3n82 NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.702
3lns NAPNAD(P)-dependent benzaldehyde dehydrogenase 1.2.1.28 0.699
4h73 NDPAldehyde dehydrogenase / 0.699
1qi1 NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1.2.1.9 0.698
4c3s NADAldehyde Dehydrogenase / 0.692
4l2o NADAldehyde dehydrogenase, dimeric NADP-preferring / 0.692
2bja NAD1-pyrroline-5-carboxylate dehydrogenase / 0.691
4f3x NADPutative aldehyde dehydrogenase / 0.690
4go2 TAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.689
4pxn NADAldehyde dehydrogenase family 7 member B4 / 0.689
3rho NAPCytosolic 10-formyltetrahydrofolate dehydrogenase 1.5.1.6 0.680
1nzx NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.672
2onm NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.672
4fqf NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.672
4wb9 NAIRetinal dehydrogenase 1 1.2.1.36 0.668
1bxs NADRetinal dehydrogenase 1 1.2.1.36 0.667
1cw3 NADAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.667
2qe0 NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1.2.1.9 0.666
3n83 ADPAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.665
4x4l NAIRetinal dehydrogenase 1 1.2.1.36 0.665
1uxu NAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase / 0.662
4zuk NADAlpha-aminoadipic semialdehyde dehydrogenase 1.2.1.31 0.662
4zz7 NADMethylmalonate-semialdehyde dehydrogenase / 0.654
1jq5 NADGlycerol dehydrogenase 1.1.1.6 0.652
4pt0 NADAldehyde dehydrogenase / 0.652
1wnb NAIGamma-aminobutyraldehyde dehydrogenase 1.2.1.19 0.651
1nzz NAIAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.650