Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4j8p FMN Flavodoxin

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4j8p FMNFlavodoxin / 1.239
3klb FMNUncharacterized protein / 1.109
1zwl FMNNAD(P)H dehydrogenase (quinone) 1.6.5.2 0.870
1kbo FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.822
1kbq FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.818
3rpe FADPutative modulator of drug activity / 0.817
2b3d FADModulator of drug activity B / 0.810
4qoe FADRibosyldihydronicotinamide dehydrogenase [quinone] / 0.809
4n9q FMNFMN-dependent NADH-azoreductase 1 / 0.808
1qbg FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.806
2hpv FMNFMN-dependent NADH-azoreductase 1.7 0.806
5f12 FMNNAD(P)H dehydrogenase (quinone) / 0.805
4zvn FADRibosyldihydronicotinamide dehydrogenase [quinone] / 0.802
1h66 FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.800
2r97 FMNNAD(P)H dehydrogenase (quinone) / 0.800
4r81 FMNPredicted NADH dehydrogenase / 0.799
4zvl FADRibosyldihydronicotinamide dehydrogenase [quinone] / 0.799
1qr2 FADRibosyldihydronicotinamide dehydrogenase [quinone] / 0.797
3g5m FADRibosyldihydronicotinamide dehydrogenase [quinone] / 0.793
1d4a FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.790
1h69 FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.788
1dxo FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.783
5eai FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.777
1gg5 FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.776
2q9u FMNA-type flavoprotein / 0.776
4dy4 FMNNAD(P)H dehydrogenase (quinone) / 0.771
5a4k FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.770
4gi5 FADPutative NAD(P)H dehydrogenase (Quinone) / 0.761
4qof FMNRibosyldihydronicotinamide dehydrogenase [quinone] / 0.761
2qmy FADRibosyldihydronicotinamide dehydrogenase [quinone] / 0.740
1t5b FMNFMN-dependent NADH-azoreductase / 0.737
4m0c FMNFMN-dependent NADH-azoreductase 1 / 0.736
4n82 FMNRibonucleotide reductase (NrdI family protein), putative / 0.733
1ycf FMNNitric oxide reductase 1 0.725
1z44 FMNNADPH dehydrogenase / 0.720
3n39 FMNProtein NrdI / 0.720
3n3a FMNProtein NrdI / 0.720
4n65 FMNFMN-dependent NADH-azoreductase 1 / 0.717
2ohi FMNType A flavoprotein FprA 1 0.711
2v5u FMNFlavodoxin / 0.705
3qe2 FMNNADPH--cytochrome P450 reductase / 0.704
2r96 FMNNAD(P)H dehydrogenase (quinone) / 0.702
3n3b FMNProtein NrdI / 0.701
1dxq FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.700
1fue FMNFlavodoxin / 0.699
4tmb FMNOld yellow enzyme / 0.695
1ofv FMNFlavodoxin / 0.692
2h8x FMNXenA / 0.692
2z9d FMNFMN-dependent NADH-azoreductase / 0.692
3hf3 FMNChromate reductase / 0.692
3w77 FMNFMN-dependent NADH-azoreductase / 0.692
3aty FMNProstaglandin F2a synthase / 0.690
1czn FMNFlavodoxin / 0.689
3hgr FMN12-oxophytodienoate reductase 1 1.3.1.42 0.689
4z9r FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD / 0.689
1ych FMNNitric oxide reductase 1 0.688
2ohh FMNType A flavoprotein FprA 1 0.688
2bn4 FMNNADPH--cytochrome P450 reductase / 0.687
2v5v FMNFlavodoxin / 0.686
4bmo FMNProtein NrdI / 0.686
4df2 FMNNADPH dehydrogenase / 0.686
4rnx FMNNADPH dehydrogenase 1 1.6.99.1 0.686
3zho FMNNAD(P)H dehydrogenase (quinone) / 0.685
4yco FMNtRNA-dihydrouridine(16) synthase / 0.685
1vcf FMNIsopentenyl-diphosphate delta-isomerase / 0.684
2ohj FMNType A flavoprotein FprA 1 0.681
2w5u FMNFlavodoxin / 0.681
3bnk FMNFlavoredoxin / 0.681
3f6s FMNFlavodoxin / 0.681
4bmp FMNProtein NrdI / 0.681
5ebu FMNLactate oxidase / 0.681
2nli FMNLactate oxidase / 0.680
1buc FADAcyl-CoA dehydrogenase, short-chain specific 1.3.8.1 0.678
3gka FMNN-ethylmaleimide reductase / 0.678
1aku FMNFlavodoxin / 0.676
1vhn FMNtRNA-dihydrouridine synthase / 0.676
2bf4 FMNNADPH--cytochrome P450 reductase / 0.676
3qfr FMNNADPH--cytochrome P450 reductase / 0.676
5a8a FMNRiboflavin biosynthesis protein RibF 2.7.1.26 0.676
1icp FMN12-oxophytodienoate reductase 1 1.3.1.42 0.675
4awt FMNNADH:flavin oxidoreductase Sye1 / 0.674
4tmc FMNOld yellow enzyme / 0.673
5a89 FMNRiboflavin biosynthesis protein RibF 2.7.1.26 0.672
1azl FMNFlavodoxin / 0.669
1udy FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.669
5cpm FNRNADH:flavin oxidoreductase / 0.669
3in6 FMNUncharacterized protein / 0.668
4b5n FMNNAD(P)H:flavin oxidoreductase Sye4 / 0.668
4y7c FMNNADPH--cytochrome P450 reductase / 0.668
4yl2 FMNLactate oxidase / 0.668
3b03 VNRIsopentenyl-diphosphate delta-isomerase / 0.667
4aws FMNNADH:flavin oxidoreductase Sye1 / 0.667
4xq6 FMNDihydroorotate dehydrogenase (quinone) / 0.667
2q3r FMN12-oxophytodienoate reductase 1 1.3.1.42 0.665
1bwk FMNNADPH dehydrogenase 1 1.6.99.1 0.664
3ojw FMNNADPH--cytochrome P450 reductase / 0.664
4hs4 FMNChromate reductase / 0.664
1tll FMNNitric oxide synthase, brain 1.14.13.39 0.663
4jic FMNGTN Reductase / 0.663
4qai FMNNADPH dehydrogenase / 0.663
2zrv FNRIsopentenyl-diphosphate delta-isomerase / 0.662
3kap FMNFlavodoxin / 0.662
3pfd FDAAcyl-CoA dehydrogenase FadE25 / 0.662
4rnw FMNNADPH dehydrogenase 1 1.6.99.1 0.662
1ea0 FMNGlutamate synthase [NADPH] large chain 1.4.1.13 0.661
1wsb FMNFlavodoxin / 0.661
1ycg FMNNitric oxide reductase 1 0.661
3k4n FADPyranose 2-oxidase / 0.661
3l67 FMNXenobiotic reductase / 0.661
4cw5 FMNDfnA / 0.661
1ger FADGlutathione reductase 1.8.1.7 0.660
2fre FMNNAD(P)H-flavin oxidoreductase / 0.660
3f6r FMNFlavodoxin / 0.660
4uth FMNXenobiotic reductase / 0.660
4utl FNRXenobiotic reductase / 0.660
2hs6 FMN12-oxophytodienoate reductase 3 1.3.1.42 0.659
2q3o FMN12-oxophytodienoate reductase 3 1.3.1.42 0.659
3l5l FMNXenobiotic reductase / 0.659
4e2d FMNDehydrogenase / 0.659
4utm FNRXenobiotic reductase / 0.659
4h6k FMNNADPH dehydrogenase 1 1.6.99.1 0.658
4k7y FMNNADPH dehydrogenase 1 1.6.99.1 0.658
4m5p FMNNADPH dehydrogenase / 0.658
5tgz FMNCannabinoid receptor 1 / 0.658
1oyc FMNNADPH dehydrogenase 1 1.6.99.1 0.657
1yob FMNFlavodoxin 2 / 0.657
2fcr FMNFlavodoxin / 0.657
2gou FMNNADH:flavin oxidoreductase Sye1 / 0.657
3lcm FADPutative oxidoreductase / 0.657
3tjl FMNNADPH dehydrogenase / 0.657
1oya FMNNADPH dehydrogenase 1 1.6.99.1 0.656
3p8j FMNPentaerythritol tetranitrate reductase / 0.656
1eje FMNProtein MTH_152 / 0.655
3hjk FADVivid PAS protein VVD / 0.655
1xyv FMNFlavodoxin / 0.654
3mkh FADNitroalkane oxidase / 0.654
4h6p FMNChromate reductase / 0.654
5cho FADFlavin reductase / 0.654
1akw FMNFlavodoxin / 0.653
1icq FMN12-oxophytodienoate reductase 1 1.3.1.42 0.653
1tdn FADL-amino-acid oxidase 1.4.3.2 0.653
1vji FMN12-oxophytodienoate reductase 1 1.3.1.42 0.653
4qnw FMNChanoclavine-I aldehyde reductase easA / 0.653
1ics FMN12-oxophytodienoate reductase 1 1.3.1.42 0.652
1j8q FMNFlavodoxin / 0.652
3c3n FMNDihydroorotate dehydrogenase (fumarate) 1.3.98.1 0.652
1qlt FADVanillyl-alcohol oxidase 1.1.3.38 0.651
1iqr FADDeoxyribodipyrimidine photo-lyase 4.1.99.3 0.650