sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4c43 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4c43 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.348 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.282 | |
| 3zbt | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.280 | |
| 1qgy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.278 | |
| 1ogi | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.264 | |
| 2b5o | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.252 | |
| 1que | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.249 | |
| 1ogj | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.248 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.247 | |
| 1qh0 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.245 | |
| 1e62 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.243 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.236 | |
| 1e64 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.234 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 1.232 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 1.230 | |
| 1gaw | FAD | Ferredoxin | / | 1.223 | |
| 1fnc | FDA | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.222 | |
| 1go2 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.220 | |
| 1gr1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.207 | |
| 1w35 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.198 | |
| 1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.196 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.196 | |
| 1fnd | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.195 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.193 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.190 | |
| 1b2r | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.189 | |
| 1fnb | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.186 | |
| 1e63 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.182 | |
| 1qg0 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 1.177 | |
| 4bpr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.163 | |
| 1bx0 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.158 | |
| 2rc5 | FAD | Ferredoxin--NADP reductase | / | 1.155 | |
| 3w5u | FAD | Ferredoxin | / | 1.138 | |
| 1h85 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.137 | |
| 1sm4 | FAD | Ferredoxin--NADP reductase | / | 1.089 | |
| 2rc6 | FAD | Ferredoxin--NADP reductase | / | 1.086 | |
| 1qgz | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.085 | |
| 1gaq | FAD | Ferredoxin | / | 1.073 | |
| 1ewy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.037 | |
| 1w87 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.031 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 1.025 | |
| 4uaj | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 1.013 | |
| 4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.985 | |
| 3ojw | FAD | NADPH--cytochrome P450 reductase | / | 0.984 | |
| 2xnc | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.982 | |
| 3qfs | FAD | NADPH--cytochrome P450 reductase | / | 0.967 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.962 | |
| 1ja1 | FAD | NADPH--cytochrome P450 reductase | / | 0.952 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.947 | |
| 4yaf | FAD | NADPH--cytochrome P450 reductase | / | 0.941 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.912 | |
| 3qe2 | FAD | NADPH--cytochrome P450 reductase | / | 0.894 | |
| 3qfc | FAD | NADPH--cytochrome P450 reductase | / | 0.892 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.879 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.877 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.877 | |
| 3w2e | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.876 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.871 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.871 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.871 | |
| 3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.860 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.856 | |
| 3qfr | FAD | NADPH--cytochrome P450 reductase | / | 0.855 | |
| 1cqx | FAD | Flavohemoprotein | / | 0.854 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.854 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.841 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.838 | |
| 4yao | FAD | NADPH--cytochrome P450 reductase | / | 0.831 | |
| 1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.822 | |
| 3jqr | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.822 | |
| 3w2f | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.822 | |
| 4y9u | FAD | NADPH--cytochrome P450 reductase | / | 0.822 | |
| 2bpo | FAD | NADPH--cytochrome P450 reductase | / | 0.815 | |
| 2r6h | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.804 | |
| 3fpk | FAD | Ferredoxin-NADP reductase | / | 0.804 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.792 | |
| 4y7c | FAD | NADPH--cytochrome P450 reductase | / | 0.792 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.786 | |
| 4y9r | FAD | NADPH--cytochrome P450 reductase | / | 0.782 | |
| 2pia | FMN | Phthalate dioxygenase reductase | / | 0.780 | |
| 1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.777 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.775 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.772 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.754 | |
| 1ep3 | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit | / | 0.744 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.729 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.702 | |
| 2iml | FMN | Uncharacterized protein | / | 0.700 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.688 | |
| 4k1x | FAD | NADPH:ferredoxin reductase | / | 0.687 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.684 | |
| 1eje | FMN | Protein MTH_152 | / | 0.682 | |
| 1i0s | FMN | Ferric-chelate reductase (NAD(P)H) | / | 0.679 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.677 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.675 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.675 | |
| 3hdy | FDA | UDP-galactopyranose mutase | / | 0.674 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.673 | |
| 1wlk | FMN | FMN-binding protein | / | 0.672 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.670 | |
| 2vnh | FAD | NADPH:ferredoxin reductase | / | 0.669 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.663 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.663 | |
| 3r5z | F42 | Uncharacterized protein | / | 0.663 | |
| 3rha | FDA | Putrescine oxidase | / | 0.662 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.661 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.661 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.660 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.660 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.659 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.659 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.657 | |
| 3mkh | FAD | Nitroalkane oxidase | / | 0.656 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.654 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.654 | |
| 4rhe | FMN | Flavin prenyltransferase UbiX | / | 0.654 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.654 | |
| 1usc | FMN | Monooxygenase | / | 0.653 | |
| 2iyi | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.653 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.652 | |
| 1wli | FMN | FMN-binding protein | / | 0.651 | |
| 2qdx | FAD | Ferredoxin--NADP+ reductase | / | 0.651 | |
| 2bgi | FAD | NADPH:ferredoxin reductase | / | 0.650 |