sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.847 | |
| 1eyn | 2AN | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.744 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.744 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.744 | |
| 1wrl | TFP | Troponin C, slow skeletal and cardiac muscles | / | 0.744 | |
| 1xrp | PRO_LEU_GLY_GLY | Proline iminopeptidase | 3.4.11.5 | 0.744 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.744 | |
| 2xvv | 9DN | Serum albumin | / | 0.744 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.744 | |
| 3gww | SFX | Na(+):neurotransmitter symporter (Snf family) | / | 0.744 | |
| 3nc9 | TR3 | Ketohexokinase | / | 0.744 | |
| 3nfa | CBJ | Gag-Pol polyprotein | / | 0.744 | |
| 3ngq | 1PS | CCR4-NOT transcription complex subunit 6-like | 3.1.13.4 | 0.744 | |
| 4c1f | X8Z | Metallo-beta-lactamase type 2 | / | 0.744 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.744 | |
| 4ivo | ACJ | Protoporphyrinogen oxidase | 1.3.3.4 | 0.744 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.744 | |
| 5dby | DIF | Serum albumin | / | 0.744 | |
| 5dby | NPS | Serum albumin | / | 0.744 | |
| 5jqb | IBP | Envelope glycoprotein | / | 0.744 | |
| 4e5j | 581 | Polymerase acidic protein | / | 0.673 | |
| 13gs | SAS | Glutathione S-transferase P | 2.5.1.18 | 0.671 | |
| 2y00 | Y01 | Beta-1 adrenergic receptor | / | 0.667 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.666 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.666 | |
| 2gm1 | 2AZ | Kinesin-like protein KIF11 | / | 0.666 | |
| 2q6h | CXX | Na(+):neurotransmitter symporter (Snf family) | / | 0.666 | |
| 3gwu | SRE | Na(+):neurotransmitter symporter (Snf family) | / | 0.666 | |
| 3p8h | P8H | Lethal(3)malignant brain tumor-like protein 1 | / | 0.666 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.666 | |
| 4as7 | 6LX | Kinesin-like protein KIF11 | / | 0.666 | |
| 4b76 | PW1 | Genome polyprotein | 3.4.21.98 | 0.666 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.666 | |
| 4jlt | 8PR | Cytochrome P450 2B4 | 1.14.14.1 | 0.666 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.666 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.665 | |
| 1rml | NTS | Fibroblast growth factor 1 | / | 0.660 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.660 | |
| 2qju | DSM | Na(+):neurotransmitter symporter (Snf family) | / | 0.660 | |
| 4fgj | 1PQ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.660 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.658 | |
| 1mdl | RMN | Mandelate racemase | / | 0.657 | |
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.654 | |
| 2hz4 | 4ST | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.652 | |
| 2q72 | IXX | Na(+):neurotransmitter symporter (Snf family) | / | 0.652 | |
| 2qei | CXX | Na(+):neurotransmitter symporter (Snf family) | / | 0.652 | |
| 4i1r | LZU | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 3.4.22 | 0.652 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.652 | |
| 4ej4 | EJ4 | Delta-type opioid receptor | / | 0.652 |