Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3pfd FDA Acyl-CoA dehydrogenase FadE25

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3pfd FDAAcyl-CoA dehydrogenase FadE25 / 1.608
2vig FADShort-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.1 1.398
1jqi FADShort-chain specific acyl-CoA dehydrogenase, mitochondrial / 1.250
4p13 FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 1.125
1rx0 FADIsobutyryl-CoA dehydrogenase, mitochondrial 1.3.99 1.082
4m9a FDAAcyl-CoA dehydrogenase / 1.054
3mdd FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 1.019
5af7 FADAcyl-CoA dehydrogenase / 0.998
2pg0 FADAcyl-CoA dehydrogenase / 0.995
5ahs FADAcyl-CoA dehydrogenase / 0.980
5jsc FADPutative acyl-CoA dehydrogenase / 0.961
3owa FADAcyl-CoA dehydrogenase / 0.958
3oib FDAPutative acyl-CoA dehydrogenase / 0.949
3p4t FAOPutative acyl-CoA dehydrogenase / 0.949
1buc FADAcyl-CoA dehydrogenase, short-chain specific 1.3.8.1 0.947
4iv6 FDAIsovaleryl-CoA dehydrogenase / 0.945
1egd FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.934
3r7k FDAProbable acyl CoA dehydrogenase / 0.924
1t9g FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.920
2d29 FADAcyl-CoA dehydrogenase / 0.912
2eba FADPutative glutaryl-CoA dehydrogenase / 0.901
4x28 FDAAcyl-CoA dehydrogenase FadE26 / 0.892
4x28 FDAAcyl-CoA dehydrogenase FadE27 / 0.892
2ix5 FADAcyl-coenzyme A oxidase 4, peroxisomal 1.3.3.6 0.856
3sf6 FDAGlutaryl-CoA dehydrogenase / 0.853
2a1t FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.840
3mpi FADGlutaryl-CoA dehydrogenase 1.3.99.32 0.837
2dvl FADAcyl-CoA dehydrogenase / 0.829
3nf4 FADAcyl-CoA dehydrogenase domain-containing protein / 0.826
1u8v FAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase / 0.816
1ege FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.797
4irn FADAnaB / 0.797
3djl FADPutative acyl-CoA dehydrogenase AidB 1.3.99 0.793
2z1q FADAcyl-CoA dehydrogenase / 0.792
1r2j FADFkbI / 0.772
3mpj FADGlutaryl-CoA dehydrogenase 1.3.99.32 0.749
2c12 FADNitroalkane oxidase 1.7.3.1 0.742
1udy FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.741
3u33 FADPutative acyl-CoA dehydrogenase AidB 1.3.99 0.729
1siq FADGlutaryl-CoA dehydrogenase, mitochondrial 1.3.8.6 0.716
2bkj FMNNADPH-flavin oxidoreductase / 0.688
4kto FADPutative isovaleryl-CoA dehydrogenase protein / 0.686
2yyi FAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component 1.14.14.9 0.685
4y9l FADAcyl-CoA dehydrogenase family member 11 / 0.681
2fon FADAcyl-coenzyme A oxidase / 0.678
2isl FNR5,6-dimethylbenzimidazole synthase 1.13.11.79 0.675
3ge6 FMNNitroreductase / 0.675
1n07 FMNRiboflavin kinase 2.7.1.26 0.672
4yus FMNFamily 3 adenylate cyclase / 0.672
3gfz FMNUncharacterized protein / 0.671
4qly FMNEnone reductase CLA-ER / 0.668
1zwl FMNNAD(P)H dehydrogenase (quinone) 1.6.5.2 0.667
1eje FMNProtein MTH_152 / 0.665
5fs7 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.665
1yki FMNOxygen-insensitive NAD(P)H nitroreductase / 0.664
3qvr FADGlucose oxidase 1.1.3.4 0.662
4j8p FMNFlavodoxin / 0.662
2c9o ADPRuvB-like 1 3.6.4.12 0.661
2gjn FMNNitronate monooxygenase 1.13.12.16 0.661
4ttc FMNIodotyrosine deiodinase 1 / 0.661
3p62 FMNPentaerythritol tetranitrate reductase / 0.659
1knp FADL-aspartate oxidase 1.4.3.16 0.658
2gew FADCholesterol oxidase 1.1.3.6 0.658
2ohj FMNType A flavoprotein FprA 1 0.658
3hgo FMN12-oxophytodienoate reductase 3 1.3.1.42 0.658
2h8x FMNXenA / 0.656
2jk6 FADTrypanothione reductase / 0.656
2byc FMNBlue-light receptor of the BLUF-family / 0.655
3f6r FMNFlavodoxin / 0.655
5ebu FMNLactate oxidase / 0.655
3dk4 FADGlutathione reductase, mitochondrial 1.8.1.7 0.654
4j57 FADThioredoxin reductase 2 1.8.1.9 0.654
4l82 FMNUncharacterized protein / 0.652
4eo3 FMNBacterioferritin comigratory protein/NADH dehydrogenase / 0.651
5a89 FMNRiboflavin biosynthesis protein RibF 2.7.1.26 0.651
1bwl FMNNADPH dehydrogenase 1 1.6.99.1 0.650
1vrq FMNSubunit alpha of sarocosine oxidase / 0.650
1vrq FMNSubunit beta of sarcosine oxidase / 0.650
3k4n FADPyranose 2-oxidase / 0.650