Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2yi5 YI5 Heat shock protein HSP 90-alpha

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2yi5 YI5Heat shock protein HSP 90-alpha / 0.948
2yi6 6QMHeat shock protein HSP 90-alpha / 0.861
2yi7 BZ8Heat shock protein HSP 90-alpha / 0.833
3eko PYUHeat shock protein HSP 90-alpha / 0.800
1yc1 4BCHeat shock protein HSP 90-alpha / 0.783
2xx2 13CATP-dependent molecular chaperone HSP82 / 0.772
2yjw YJWHeat shock protein HSP 90-alpha / 0.769
2cct 2E1Heat shock protein HSP 90-alpha / 0.768
2xd6 XD6ATP-dependent molecular chaperone HSP82 / 0.764
4ce1 7FKATP-dependent molecular chaperone HSP82 / 0.758
3ekr PY9Heat shock protein HSP 90-alpha / 0.755
2byi 2DDHeat shock protein HSP 90-alpha / 0.754
4bqj XKLHeat shock protein HSP 90-alpha / 0.754
2xx4 13IATP-dependent molecular chaperone HSP82 / 0.752
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
2xab VHDHeat shock protein HSP 90-alpha / 0.742
3k99 PFTHeat shock protein HSP 90-alpha / 0.738
2cgf P2NATP-dependent molecular chaperone HSP82 / 0.730
3inw JZBHeat shock protein HSP 90-alpha / 0.727
2vcj 2EQHeat shock protein HSP 90-alpha / 0.726
4egk RDCHeat shock protein HSP 90-alpha / 0.726
2iws NP4ATP-dependent molecular chaperone HSP82 / 0.724
4ce2 BO5ATP-dependent molecular chaperone HSP82 / 0.719
2ye4 2FYHeat shock protein HSP 90-alpha / 0.714
2xjx XJXHeat shock protein HSP 90-alpha / 0.713
3hek BD0Heat shock protein HSP 90-alpha / 0.710
2ccu 2D9Heat shock protein HSP 90-alpha / 0.709
2yk2 YJWHeat shock protein HSP 90-alpha / 0.700
4efu EFUHeat shock protein HSP 90-alpha / 0.700
3k98 1RCHeat shock protein HSP 90-alpha / 0.697
4egh 0OYHeat shock protein HSP 90-alpha / 0.695
1u0z RDCEndoplasmin / 0.690
2wer RDCATP-dependent molecular chaperone HSP82 / 0.685
2uwd 2GGHeat shock protein HSP 90-alpha / 0.678
1qy8 RDIEndoplasmin / 0.674
2byh 2D7Heat shock protein HSP 90-alpha / 0.674
2gfd RDAEndoplasmin / 0.674
3ti1 B49Cyclin-dependent kinase 2 2.7.11.22 0.661
4e5f 0N7Polymerase acidic protein / 0.660
2bsm BSMHeat shock protein HSP 90-alpha / 0.659
1bgq RDCATP-dependent molecular chaperone HSP82 / 0.658
1fuy FIPTryptophan synthase alpha chain / 0.656
1qip GNBLactoylglutathione lyase 4.4.1.5 0.654
2bre KJ2ATP-dependent molecular chaperone HSP82 / 0.652
2xjj L81Heat shock protein HSP 90-alpha / 0.652
3k3i I46Mitogen-activated protein kinase 14 / 0.652
3ncg BK1Calmodulin-domain protein kinase 1, putative / 0.651