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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2y00 Y01 Beta-1 adrenergic receptor

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2y00 Y01Beta-1 adrenergic receptor / 1.364
2y02 Y01Beta-1 adrenergic receptor / 1.291
2y01 Y01Beta-1 adrenergic receptor / 1.129
2y03 Y01Beta-1 adrenergic receptor / 1.081
1v2h GUNPurine nucleoside phosphorylase 2.4.2.1 0.744
2puc GUNHTH-type transcriptional repressor PurR / 0.744
4e5i 0N9Polymerase acidic protein / 0.744
4e5l DBHPolymerase acidic protein / 0.744
4ek9 EP4Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.744
1n38 U3HRNA-directed RNA polymerase lambda-3 2.7.7.48 0.681
1drt PCVClavaminate synthase 1 1.14.11.21 0.678
4nky 3QZSteroid 17-alpha-hydroxylase/17,20 lyase / 0.672
1fdu ESTEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.667
3ty3 GGGHomoisocitrate dehydrogenase 1.1.1.87 0.667
1lri CLRBeta-elicitin cryptogein / 0.663
1jtv TESEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.661
1ozq PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1p0e PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1ulb GUNPurine nucleoside phosphorylase 2.4.2.1 0.660
2pwu GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
2z1x PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
3bld PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4e5f 0N7Polymerase acidic protein / 0.660
4gcx PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4hqv QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4hvx QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.655
1xu9 CPSCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.655