Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2qhm 7CS Serine/threonine-protein kinase Chk1 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2qhm 7CSSerine/threonine-protein kinase Chk1 2.7.11.1 0.819
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
1zys 199Serine/threonine-protein kinase Chk1 2.7.11.1 0.739
4e6d 0NUTyrosine-protein kinase JAK2 / 0.703
3sc1 3S13-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.701
3zls 92PDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.691
2wmw ZYWSerine/threonine-protein kinase Chk1 2.7.11.1 0.690
1jpa ANPEphrin type-B receptor 2 2.7.10.1 0.680
1q8t Y27cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.668
2z7q ACPRibosomal protein S6 kinase alpha-1 2.7.11.1 0.664
4e5f 0N7Polymerase acidic protein / 0.660
1nvr STUSerine/threonine-protein kinase Chk1 2.7.11.1 0.659
4oti MI1Serine/threonine-protein kinase N1 / 0.659
2cgw 3C3Serine/threonine-protein kinase Chk1 2.7.11.1 0.658
4bid IE8Mitogen-activated protein kinase kinase kinase 5 2.7.11.25 0.651