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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1sa5 BMV Protein farnesyltransferase subunit beta 2.5.1.58

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1sa5 BMVProtein farnesyltransferase subunit beta 2.5.1.58 0.851
1efz PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.744
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
1m3q ANGN-glycosylase/DNA lyase 3.2.2 0.744
1v2h GUNPurine nucleoside phosphorylase 2.4.2.1 0.744
2puc GUNHTH-type transcriptional repressor PurR / 0.744
4ek9 EP4Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.744
3pz4 3PZProtein farnesyltransferase subunit beta 2.5.1.58 0.741
4gtm 7TMProtein farnesyltransferase subunit beta 2.5.1.58 0.731
3e33 ED7Protein farnesyltransferase subunit beta 2.5.1.58 0.698
4gtp 7TPProtein farnesyltransferase subunit beta 2.5.1.58 0.680
4gtv 7TRGeranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.678
4gtr 7TRProtein farnesyltransferase subunit beta 2.5.1.58 0.672
2r2l PB9Protein farnesyltransferase subunit beta 2.5.1.58 0.671
3pz2 3PZGeranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.665
4gts 7TPGeranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.661
1ozq PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1ulb GUNPurine nucleoside phosphorylase 2.4.2.1 0.660
2pot GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
2pwu GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
2z1x PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
3bld PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4gcx PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4h7z GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4hqv QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
3q7f ED2Uncharacterized protein / 0.653