Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1lsj NAD Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1lsj NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 1.007
1f17 NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.738
3zw9 NADPeroxisomal bifunctional enzyme 1.1.1.35 0.735
4kug NAD3-hydroxybutyryl-CoA dehydrogenase / 0.726
3had NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.724
2oxi NADAlcohol dehydrogenase E chain 1.1.1.1 0.719
1ht0 NADAlcohol dehydrogenase 1C 1.1.1.1 0.715
1u3v NADAlcohol dehydrogenase 1B 1.1.1.1 0.715
1dc6 NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.712
4ng5 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.707
4dl9 NADS-(hydroxymethyl)glutathione dehydrogenase / 0.706
5cdg NAJAlcohol dehydrogenase E chain 1.1.1.1 0.706
5kcp NAJAlcohol dehydrogenase E chain 1.1.1.1 0.705
5kcz NAJAlcohol dehydrogenase E chain 1.1.1.1 0.705
5kj1 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.705
2ohx NADAlcohol dehydrogenase E chain 1.1.1.1 0.704
3oq6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.704
4dwv NAJAlcohol dehydrogenase E chain 1.1.1.1 0.704
4dxh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.704
4nfh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.704
5cds NAJAlcohol dehydrogenase E chain 1.1.1.1 0.704
5cdt NAJAlcohol dehydrogenase E chain 1.1.1.1 0.704
5kj6 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.704
5kje NAJAlcohol dehydrogenase E chain 1.1.1.1 0.704
2hdh NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.703
1guy NADMalate dehydrogenase / 0.697
1lua NAPBifunctional protein MdtA 1.5.1.5 0.696
3pef NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.695
1het NADAlcohol dehydrogenase E chain 1.1.1.1 0.693
3wmx NADNAD dependent epimerase/dehydratase / 0.693
1mgo NADAlcohol dehydrogenase E chain 1.1.1.1 0.692
2jhf NADAlcohol dehydrogenase E chain 1.1.1.1 0.689
5kjf NAJAlcohol dehydrogenase E chain 1.1.1.1 0.688
2yy7 NADL-threonine dehydrogenase / 0.686
2i9p NAD3-hydroxyisobutyrate dehydrogenase, mitochondrial 1.1.1.31 0.685
4om8 NAD3-hydroxybutyryl-coA dehydrogenase / 0.684
4plp NADHomospermidine synthase 2.5.1.44 0.683
5kjc NAJAlcohol dehydrogenase E chain 1.1.1.1 0.683
2vhx NADAlanine dehydrogenase 1.4.1.1 0.682
2dt5 NADRedox-sensing transcriptional repressor Rex / 0.680
1cdo NADAlcohol dehydrogenase 1 1.1.1.1 0.677
4xrg NADHomospermidine synthase 2.5.1.44 0.677
4nfs NAJAlcohol dehydrogenase E chain 1.1.1.1 0.676
2pa3 NAID-3-phosphoglycerate dehydrogenase 1.1.1.95 0.675
1nqo NADGlyceraldehyde-3-phosphate dehydrogenase / 0.674
4xd2 NAIAlcohol dehydrogenase E chain 1.1.1.1 0.674
1bdb NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase / 0.673
1cer NADGlyceraldehyde-3-phosphate dehydrogenase / 0.673
1heu NADAlcohol dehydrogenase E chain 1.1.1.1 0.673
1wwk NAD307aa long hypothetical phosphoglycerate dehydrogenase / 0.673
3pdu NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.673
4rls NAIL-lactate dehydrogenase A chain 1.1.1.27 0.673
3f3s NADLambda-crystallin homolog / 0.672
4xqc NADHomospermidine synthase 2.5.1.44 0.672
1f8f NADBenzyl alcohol dehydrogenase / 0.670
1geg NADDiacetyl reductase [(S)-acetoin forming] 1.1.1.304 0.670
5lc1 NADL-threonine 3-dehydrogenase / 0.666
1adc PADAlcohol dehydrogenase E chain 1.1.1.1 0.665
1axe NADAlcohol dehydrogenase E chain 1.1.1.1 0.665
4lsm NADGlyceraldehyde-3-phosphate dehydrogenase / 0.665
4yr9 NADL-threonine 3-dehydrogenase, mitochondrial 1.1.1.103 0.665
2fzw NADAlcohol dehydrogenase class-3 1.1.1.1 0.664
1m76 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.663
1mp0 NADAlcohol dehydrogenase class-3 1.1.1.1 0.663
3w8e NAD3-hydroxybutyrate dehydrogenase / 0.663
2hun NAD336aa long hypothetical dTDP-glucose 4,6-dehydratase / 0.661
2iyp NAP6-phosphogluconate dehydrogenase, decarboxylating 1.1.1.44 0.661
1gyp NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal 1.2.1.12 0.660
3cos NADAlcohol dehydrogenase 4 1.1.1.1 0.660
3m2t NADProbable dehydrogenase / 0.659
1a71 NADAlcohol dehydrogenase E chain 1.1.1.1 0.658
1lde NADAlcohol dehydrogenase E chain 1.1.1.1 0.658
4wji NAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase / 0.658
1e3l NADAlcohol dehydrogenase 4 1.1.1.1 0.657
1il0 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.657
1m75 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.657
2ztu NADD(-)-3-hydroxybutyrate dehydrogenase / 0.657
1f0y NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.655
4xr9 NADCalS8 / 0.655
1o6z NADMalate dehydrogenase / 0.654
1sc6 NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.654
3vdq NAD3-hydroxybutyrate dehydrogenase / 0.654
3zcx NADGlyceraldehyde-3-phosphate dehydrogenase / 0.654
4xq9 NADHomospermidine synthase 2.5.1.44 0.654
1lso NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.653
1e3s NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.652
1hf3 NADAlcohol dehydrogenase E chain 1.1.1.1 0.652
1kol NADGlutathione-independent formaldehyde dehydrogenase / 0.652
1znq NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.651
4k28 NADShikimate dehydrogenase family protein / 0.651
2o4c NADErythronate-4-phosphate dehydrogenase / 0.650
4cpd NADAlcohol dehydrogenase / 0.650