sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1efp | FAD | Electron transfer flavoprotein subunit alpha |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1efp | FAD | Electron transfer flavoprotein subunit alpha | / | 1.522 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 1.304 | |
| 2a1u | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 1.232 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 1.125 | |
| 3clt | FAD | Electron transfer flavoprotein subunit alpha | / | 1.110 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 1.109 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 1.092 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 1.044 | |
| 4hj3 | FMN | LOV protein | / | 0.752 | |
| 4eeu | FMN | Phototropin-2 | 2.7.11.1 | 0.735 | |
| 1x0p | FAD | Tll0078 protein | / | 0.734 | |
| 4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.729 | |
| 2pr5 | FMN | Blue-light photoreceptor | / | 0.728 | |
| 4hj4 | FMN | LOV protein | / | 0.725 | |
| 5ahk | FAD | Acetolactate synthase II, large subunit | / | 0.718 | |
| 3ea4 | FAB | Acetolactate synthase, chloroplastic | 2.2.1.6 | 0.717 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.714 | |
| 4hia | FMN | LOV protein | / | 0.714 | |
| 2pan | FAD | Glyoxylate carboligase | 4.1.1.47 | 0.713 | |
| 1jsc | FAD | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.712 | |
| 2iyi | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.712 | |
| 4hj6 | FMN | LOV protein | / | 0.710 | |
| 2gj3 | FAD | Nitrogen fixation regulatory protein | 2.7.13.3 | 0.706 | |
| 2v0u | FMN | NPH1-1 | / | 0.706 | |
| 4wuj | FMN | Glycoside hydrolase family 15, cellulose signaling associated protein envoy | / | 0.706 | |
| 2vnh | FAD | NADPH:ferredoxin reductase | / | 0.704 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.701 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.701 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.700 | |
| 4eer | FMN | Phototropin-2 | 2.7.11.1 | 0.700 | |
| 3e9y | FAB | Acetolactate synthase, chloroplastic | 2.2.1.6 | 0.699 | |
| 1n9l | FMN | Putative blue light receptor | / | 0.698 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.698 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.696 | |
| 2v1a | FMN | NPH1-1 | / | 0.696 | |
| 2vnk | FAD | NADPH:ferredoxin reductase | / | 0.695 | |
| 2iyg | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.694 | |
| 3gfx | FMN | Uncharacterized protein | / | 0.694 | |
| 4kuo | RBF | Putative blue-light photoreceptor | / | 0.694 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.693 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.690 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.689 | |
| 4hh0 | FMN | AppA protein | / | 0.687 | |
| 1m2j | APR | NAD-dependent protein deacylase 1 | / | 0.684 | |
| 1m2g | APR | NAD-dependent protein deacylase 1 | / | 0.683 | |
| 1i0s | FMN | Ferric-chelate reductase (NAD(P)H) | / | 0.682 | |
| 2dji | FAD | Pyruvate oxidase | / | 0.681 | |
| 4yus | FMN | Family 3 adenylate cyclase | / | 0.681 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.676 | |
| 5d7q | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.676 | |
| 3m31 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.675 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.674 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.673 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.673 | |
| 5d7o | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.673 | |
| 2vnj | FAD | NADPH:ferredoxin reductase | / | 0.672 | |
| 3jqr | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.672 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.671 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.670 | |
| 4bvb | AR6 | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.670 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.668 | |
| 1eje | FMN | Protein MTH_152 | / | 0.667 | |
| 1v5e | FAD | Pyruvate oxidase | / | 0.667 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.667 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.666 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.665 | |
| 4hmx | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.663 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.663 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.662 | |
| 2byc | FMN | Blue-light receptor of the BLUF-family | / | 0.660 | |
| 3a3b | RBF | Lumazine protein | / | 0.660 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.658 | |
| 3mzi | FMN | Activator of photopigment and puc expression | / | 0.656 | |
| 4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.656 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.656 | |
| 2pia | FMN | Phthalate dioxygenase reductase | / | 0.655 | |
| 3hjk | FAD | Vivid PAS protein VVD | / | 0.655 | |
| 1m2k | APR | NAD-dependent protein deacylase 1 | / | 0.651 | |
| 3gfz | FMN | Uncharacterized protein | / | 0.650 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.650 |