Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5dwqSFGHistone-arginine methyltransferase CARM1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5dwqSFGHistone-arginine methyltransferase CARM1/1.000
5dxjSFGHistone-arginine methyltransferase CARM1/0.658
2y1xSAHHistone-arginine methyltransferase CARM1/0.628
2y1wSFGHistone-arginine methyltransferase CARM1/0.619
5dx8SFGHistone-arginine methyltransferase CARM1/0.611
3b3fSAHHistone-arginine methyltransferase CARM1/0.597
1f3lSAHProtein arginine N-methyltransferase 3/0.558
5dx1SFGHistone-arginine methyltransferase CARM1/0.556
5dxaSFGHistone-arginine methyltransferase CARM1/0.554
4c03SFGProtein arginine N-methyltransferase 6/0.548
4ax8SAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.474
4mwzSAMPhosphoethanolamine N-methyltransferase, putative/0.474
2v74SAHHistone-arginine methyltransferase CARM1/0.473
4eueNAITrans-2-enoyl-CoA reductase [NADH]/0.468
3uj8SFGPhosphoethanolamine N-methyltransferase/0.465
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.463
4r6xSAHPhosphoethanolamine N-methyltransferase/0.463
4twnB96Ephrin type-A receptor 32.7.10.10.458
4fgzSAHPhosphoethanolamine N-methyltransferase/0.455
1p4mADPRiboflavin kinase2.7.1.260.454
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.454
3ou7SAMSAM-dependent methyltransferase/0.452
4dk70KSOxysterols receptor LXR-beta/0.452
5dstSAHProtein arginine N-methyltransferase 82.1.10.452
1pqc444Oxysterols receptor LXR-beta/0.451
2xuoTZ4Acetylcholinesterase3.1.1.70.451
1e66HUXAcetylcholinesterase3.1.1.70.450
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.449
1nhkCMPNucleoside diphosphate kinase2.7.4.60.449
4b66NAPL-ornithine N(5)-monooxygenase/0.449
4jq4IMNAldo-keto reductase family 1 member C2/0.449
1ny2ARG_PRO_PRO_GLYProthrombin3.4.21.50.448
1f5fDHTSex hormone-binding globulin/0.447
2bxtC2DProthrombin3.4.21.50.447
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.447
5hq8SAHHistone-lysine N-methyltransferase SMYD32.1.1.430.447
1lkeDOGBilin-binding protein/0.446
1pq944BOxysterols receptor LXR-beta/0.446
4ho4THMGlucose-1-phosphate thymidylyltransferase/0.446
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.445
1sreHABStreptavidin/0.445
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.445
1culFOKAdenylate cyclase type 2/0.444
1culFOKAdenylate cyclase type 5/0.444
3w8eNAD3-hydroxybutyrate dehydrogenase/0.444
4y1bNAPAntE/0.444
5dibNADBetaine-aldehyde dehydrogenase/0.444
1nbiSAMGlycine N-methyltransferase2.1.1.200.443
2rtoIMIStreptavidin/0.443
2zscBTNTamavidin2/0.442
3mauPLRPutative sphingosine-1-phosphate lyase/0.442
4dvi2IWTankyrase-12.4.2.300.442
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.441
3oe5611Catechol O-methyltransferase2.1.1.60.441
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.440
1srfMTBStreptavidin/0.440
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.440