Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5av3KMPDeath-associated protein kinase 12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5av3KMPDeath-associated protein kinase 12.7.11.11.000
5av2KMPDeath-associated protein kinase 12.7.11.10.802
3gu7ADPDeath-associated protein kinase 12.7.11.10.634
1jklANPDeath-associated protein kinase 12.7.11.10.616
2yaaATPDeath-associated protein kinase 2/0.573
1ig1ANPDeath-associated protein kinase 12.7.11.10.559
3bqr4RBDeath-associated protein kinase 3/0.557
5aut2ANDeath-associated protein kinase 12.7.11.10.552
2w4jADPDeath-associated protein kinase 12.7.11.10.551
1jkkANPDeath-associated protein kinase 12.7.11.10.517
2ckeIQUDeath-associated protein kinase 2/0.499
3gu83GUDeath-associated protein kinase 12.7.11.10.493
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.488
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.482
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.477
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.470
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.469
3dqwAGSProto-oncogene tyrosine-protein kinase Src2.7.10.20.465
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.464
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.461
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.460
4ysjADPCalmodulin-like domain protein kinase/0.458
3lltANPProtein serine/threonine kinase-1/0.457
4grb0XGCasein kinase II subunit alpha2.7.11.10.457
5cvfATPCasein kinase II subunit alpha2.7.11.10.455
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.454
3juhANPCasein kinase II subunit alpha2.7.11.10.453
4qnyANPMitogen activated protein kinase, putative/0.448
3at4CCKCasein kinase II subunit alpha2.7.11.10.447
3lpbNVBTyrosine-protein kinase JAK2/0.446
4hvi19STyrosine-protein kinase JAK32.7.10.20.444
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.442
4bbfO19Tyrosine-protein kinase JAK2/0.441
4hge15VTyrosine-protein kinase JAK2/0.441
3pe2E1BCasein kinase II subunit alpha2.7.11.10.440
4e4n0NLTyrosine-protein kinase JAK1/0.440
4j99ACPFibroblast growth factor receptor 2/0.440