Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4psgNOHThymidylate synthase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4psgNOHThymidylate synthase/1.000
4irrUMPThymidylate synthase/0.574
4eb4UMPThymidylate synthase2.1.1.450.569
5by6UMPThymidylate synthase/0.556
3qj7UMPThymidylate synthase ThyA/0.554
4e5oUMPThymidylate synthase2.1.1.450.546
4h0uUMPThymidylate synthase/0.546
1bidUMPThymidylate synthase/0.523
3dg8UMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.521
4xsdUMPThymidylate synthase2.1.1.450.520
3hb8UMPThymidylate synthase2.1.1.450.516
1ci7UMPThymidylate synthase2.1.1.450.512
3dgaUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.510
4einNOHThymidylate synthase2.1.1.450.509
1tsxUMPThymidylate synthase/0.508
2g86UMPThymidylate synthase/0.507
1jmgUMPThymidylate synthase/0.498
4dpdUMPBifunctional dihydrofolate reductase-thymidylate synthase/0.493
1njaDCMThymidylate synthase/0.489
1aobDDUThymidylate synthase/0.488
1bp6UMPThymidylate synthase/0.486
1njbUMPThymidylate synthase/0.486
2g89UMPThymidylate synthase/0.486
1bduDURThymidylate synthase/0.478
1an5CB3Thymidylate synthase/0.477
1f4eTPRThymidylate synthase/0.476
4dq1UMPThymidylate synthase/0.474
1vzdCB3Thymidylate synthase/0.473
2vetUMPThymidylate synthase/0.465
1vzbUMPThymidylate synthase/0.464
1jmhUMPThymidylate synthase/0.463
1njdUMPThymidylate synthase/0.463
3bgxTMPThymidylate synthase/0.462
1tsvUMPThymidylate synthase/0.461
1njcDCMThymidylate synthase/0.460
1thyUMPThymidylate synthase/0.460
1dduDDUThymidylate synthase/0.456
1jmiUMPThymidylate synthase/0.454
1tsyUMPThymidylate synthase/0.453
4fogC2FThymidylate synthase ThyA/0.451
1njeDCMThymidylate synthase/0.449
3bgxMEFThymidylate synthase/0.447
4foxUMPThymidylate synthase ThyA/0.447
1lcbTMPThymidylate synthase/0.444
4lrrCF9Thymidylate synthase/0.443
3bhlTHGThymidylate synthase/0.442
1lcbDHFThymidylate synthase/0.440