sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 1.000 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.844 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.635 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.628 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.530 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.520 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.517 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.516 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.516 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.511 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.507 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.504 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.502 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.502 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.501 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.500 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.500 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.499 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.498 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.496 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.496 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.493 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.493 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.492 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.492 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.491 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.491 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.491 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.490 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.490 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.488 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.486 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.485 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.484 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.484 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.484 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.483 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.482 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.481 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.481 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.481 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.480 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.480 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.479 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.476 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.476 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.475 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.466 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.464 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.460 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.460 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.457 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.457 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3wec | AUI | Cytochrome P450 | / | 0.455 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.454 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.450 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.450 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.447 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.444 | |
| 4egn | TWO | Cytochrome P450 | / | 0.443 |