sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ggz | BTN | Bll1558 protein |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4ggz | BTN | Bll1558 protein | / | 1.000 | |
| 1nc9 | IMI | Streptavidin | / | 0.550 | |
| 3wyp | BSO | Streptavidin | / | 0.517 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.504 | |
| 4z28 | BTN | Hoefavidin | / | 0.499 | |
| 1ndj | BTN | Streptavidin | / | 0.495 | |
| 1swn | BTN | Streptavidin | / | 0.489 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 3t2w | BTN | Avidin/streptavidin | / | 0.473 | |
| 1sre | HAB | Streptavidin | / | 0.471 | |
| 2avi | BTN | Avidin | / | 0.470 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.469 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 1swp | BTQ | Streptavidin | / | 0.468 | |
| 2izh | BTN | Streptavidin | / | 0.467 | |
| 2rti | GLL | Streptavidin | / | 0.465 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.464 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 1swt | BTN | Streptavidin | / | 0.461 | |
| 1rxh | BNI | Streptavidin | / | 0.460 | |
| 1n9m | BTN | Streptavidin | / | 0.459 | |
| 2izf | BTN | Streptavidin | / | 0.458 | |
| 2izk | GLL | Streptavidin | / | 0.458 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.457 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.456 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1stp | BTN | Streptavidin | / | 0.453 | |
| 1srf | MTB | Streptavidin | / | 0.452 | |
| 4bx7 | B4F | Streptavidin | / | 0.451 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1mk5 | BTN | Streptavidin | / | 0.448 | |
| 2rtn | IMI | Streptavidin | / | 0.448 | |
| 3ry2 | BTN | Streptavidin | / | 0.448 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.447 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.443 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.443 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.442 | |
| 3wyq | BTN | Streptavidin | / | 0.442 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.441 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3vgw | NVZ | Avidin | / | 0.441 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.441 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.440 |