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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.17

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.171.000
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.625
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.567
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.535
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.510
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.493
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.479
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.477
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.476
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.476
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.461
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.455
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.449
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.441